Evidence map›Paper›PMID 25469520›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2015

Estimating the cost of increasing retention in care for HIV-infected patients: results of the CDC/HRSA retention in care trial.

Ram K Shrestha, Lytt Gardner, Gary Marks, Jason Craw, Faye Malitz, Thomas P Giordano, Meg Sullivan, Jeanne Keruly, Allan Rodriguez, Tracey E Wilson and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ram K Shrestha*Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA; †HIV/AIDS Bureau, Health Resources and Services Administration, Rockville, MD; ‡Department of Medicine, Baylor College of Medicine, Houston, TX; §Center for Innovations in Quality, Effectiveness, and Safety, Michael E. DeBakey VA Medical Center, Houston, TX; ‖Department of Medicine, Boston University School of Medicine, Boston, MA; ¶Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; #Division of Infectious Diseases, Miller School of Medicine, University of Miami, Miami, FL; **Department of Community Health Sciences, SUNY Downstate Medical Center School of Public Health, Brooklyn, NY; and ††Division of Infectious Diseases, Department of Medicine, University of Alabama-Birmingham, Birmingham, AL.
Lytt Gardner
Gary Marks
Jason Craw
Faye Malitz
Thomas P Giordano
Meg Sullivan
Jeanne Keruly
Allan Rodriguez
Tracey E Wilson
Michael Mugavero

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GWENDOLYN Barbara SCOTT · 2007 to 2026
$33.8M
NIAID NIH HHS P30 AI073961
6 · The paper itself

Abstract

backgroundRetaining HIV patients in medical care promotes access to antiretroviral therapy, viral load suppression, and reduced HIV transmission to partners. We estimate the programmatic costs of a US multisite randomized controlled trial of an intervention to retain HIV patients in care.

methodsSix academically affiliated HIV clinics randomized patients to intervention (enhanced personal contact with patients across time coupled with basic HIV education) and control [standard of care (SOC)] arms. Retention in care was defined as 4-month visit constancy, that is, at least 1 primary care visit in each 4-month interval over a 12-month period. We used microcosting methods to collect unit costs and measure the quantity of resources used to implement the intervention in each clinic. All fixed and variable labor and nonlabor costs of the intervention were included.

resultsVisit constancy was achieved by 45.7% (280/613) of patients in the SOC arm and by 55.8% (343/615) of patients in the intervention arm, representing an increase of 63 patients (relative improvement 22.1%; 95% confidence interval: 9% to 36%; P < 0.01). The total annual cost of the intervention at the 6 clinics was $241,565, the average cost per patient was $393, and the estimated cost per additional patient retained in care beyond SOC was $3834.

conclusionsOur analyses showed that a retention in care intervention consisting of enhanced personal contact coupled with basic HIV education may be delivered at fairly low cost. These results provide useful information for guiding decisions about planning or scaling-up retention in care interventions for HIV-infected patients.

Indexed as

Drug MonitoringHealth Care CostsAdolescentAdultAgedBehavior TherapyDelivery of Health CareFemaleHIV InfectionsHumansMaleMiddle AgedPatient Education as TopicUnited StatesYoung Adult

Identifiers

PMID25469520
PMCPMC4886740

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.