Evidence map›Paper›PMID 25469254›Full record

ArticleBiomedical reports2015

Association of a genetic variant of the ZPR1 zinc finger gene with type 2 diabetes mellitus.

Fumitaka Tokoro, Reiko Matsuoka, Shintaro Abe, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Biomedical reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. [Effect of low-dose ethanol consumption on expression of nuclear factor-κB in diabetic rats with myocardial injury].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
  8. Article
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  11. Association ofBiomedical reports · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Fumitaka TokoroDepartment of Cardiology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan.
Reiko MatsuokaDepartment of Cardiology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan.
Shintaro AbeDepartment of Cardiology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan.
Masazumi AraiDepartment of Cardiology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan.
Toshiyuki NodaDepartment of Cardiology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan.
Sachiro WatanabeDepartment of Cardiology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan.
Hideki HoribeDepartment of Cardiovascular Medicine, Gifu Prefectural Tajimi Hospital, Tajimi, Gifu 507-8522, Japan.
Tetsuo FujimakiDepartment of Cardiovascular Medicine, Inabe General Hospital, Inabe, Mie 511-0428, Japan.
Mitsutoshi OguriDepartment of Cardiology, Japanese Red Cross Nagoya First Hospital, Nagoya, Aichi 453-8511, Japan.
Kimihiko KatoDepartment of Internal Medicine, Meitoh Hospital, Nagoya, Aichi 465-0025, Japan.
Shinya MinatoguchiDepartment of Cardiology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Yoshiji YamadaDepartment of Human Functional Genomics, Life Science Research Center, Mie University, Tsu, Mie 514-8507, Japan.
Gifu Prefectural General Medical Center · JPGifu Prefectural Tajimi Hospital · JPGifu University · JPMeitetsu Hospital · JPMie University · JPShowa Inan General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various loci and genes that confer susceptibility to coronary heart disease (CHD) have been identified in Caucasian populations by genome-wide association studies (GWASs). As type 2 diabetes mellitus (DM) is an important risk factor for CHD, we hypothesized that certain polymorphisms may contribute to the genetic susceptibility to CHD through affecting the susceptibility to type 2 DM. The purpose of the present study was to examine a possible association of type 2 DM in Japanese individuals with 29 polymorphisms identified as susceptibility loci for CHD by meta-analyses of the GWASs. The study subjects comprised of 3,757 individuals (1,444 subjects with type 2 DM and 2,313 controls). The polymorphism genotypes were determined by the multiplex bead-based Luminex assay, which combines the polymerase chain reaction and sequence-specific oligonucleotide probes with suspension array technology. To compensate for multiple comparisons of genotypes, the criterion of a false discovery rate (FDR) ≤0.05 was adopted for testing the statistical significance of the association. The comparisons of allele frequencies by the χ

Indexed as

diabetes mellitusgeneticspolymorphismZPR1 zinc finger gene

Identifiers

PMID25469254
PMCPMC4251148
OpenAlexW2130983912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.