ArticleF1000Research2014
Pandemic 2009 Influenza A (H1N1) virus infection in cancer and hematopoietic stem cell transplant recipients; a multicenter observational study.
Article in F1000Research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Differences in Outcomes and Factors Associated With Mortality Among Patients With SARS-CoV-2 Infection and Cancer Compared With Those Without Cancer: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- The effect of anticancer treatment on cancer patients with COVID-19: A systematic review and meta-analysis.Cancer medicine · 2021Pooled it
- A pilot randomized trial of adjuvanted influenza vaccine in adult allogeneic hematopoietic stem cell transplant recipients.Bone marrow transplantation · 2017Trial
- Stress Management Interventions to Facilitate Psychological and Physiological Adaptation and Optimal Health Outcomes in Cancer Patients and Survivors.Annual review of psychology · 2023Review
- Impact of COVID-19 on Cancer-Related Care in the United States: An Overview.Current oncology (Toronto, Ont.) · 2023Review
- The mortality rate of COVID-19 was high in cancer patients: a retrospective single-center study.International journal of clinical oncology · 2021Article
- Dealing with lung cancer in the COVID-19 scenario (A review).Molecular and clinical oncology · 2021Review
- The Sum of Fears in Cancer Patients Inside the Context of the COVID-19.Frontiers in psychiatry · 2021Review
- Collateral effects of the coronavirus disease 2019 pandemic on lung cancer diagnosis in Korea.BMC cancer · 2020Article
- How to Use a Prioritised Approach for Treating Hematological Disorders During the COVID-19 Pandemic in India?Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020Review
- How We Manage Patients With Chronic Lymphocytic Leukemia During the SARS-CoV-2 Pandemic.HemaSphere · 2020Review
- Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System.Cancer discovery · 2020Article
- A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group.The oncologist · 2020Review
- [The Effects and Management of Viral Pneumonia on Lung Cancer Patients].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020Review
- Influenza in patients with cancer after 2009 pandemic AH1N1: An 8-year follow-up study in Mexico.Influenza and other respiratory viruses · 2020Article
- Review
- Progress in Treatment of Viral Infections in Children with Acute Lymphoblastic Leukemia.Oncology reviews · 2016Review
- Influenza and Pneumococcal Vaccination in Hematological Malignancies: a Systematic Review of Efficacy, Effectiveness, and Safety.Mediterranean journal of hematology and infectious diseases · 2016Review
Corrections and comments
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Authors and funding
17 authors at 11 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring March 2009 a novel Influenza A virus emerged in Mexico. We describe the clinical picture of the pandemic Influenza A (H1N1) Influenza in cancer patients during the 2009 influenza season.
methodsTwelve centers participated in a multicenter retrospective observational study of cancer patients with confirmed infection with the 2009 H1N1 Influenza A virus (influenza-like illness or pneumonia plus positive PCR for the 2009 H1N1 Influenza A virus in respiratory secretions). Clinical data were obtained by retrospective chart review and analyzed.
resultsFrom May to August 2009, data of 65 patients were collected. Median age was 51 years, 57 % of the patients were female. Most patients (47) had onco-hematological cancers and 18 had solid tumors. Cancer treatment mainly consisted of chemotherapy (46), or stem cell transplantation (SCT) (16). Only 19 of 64 patients had received the 2009 seasonal Influenza vaccine. Clinical presentation included pneumonia (43) and upper respiratory tract infection (22). Forty five of 58 ambulatory patients were admitted. Mechanical ventilation was required in 12 patients (18%). Treatment included oseltamivir monotherapy or in combination with amantadine for a median of 7 days. The global 30-day mortality rate was 18%. All 12 deaths were among the non-vaccinated patients. No deaths were observed among the 19 vaccinated patients. Oxygen saturation <96% at presentation was a predictor of mortality (OR 19.5; 95%CI: 2.28 to 165.9).
conclusionsIn our cancer patient population, the pandemic 2009 Influenza A (H1N1) virus was associated with high incidence of pneumonia (66%), and 30-day mortality (18.5%). Saturation <96% was significantly associated with death. No deaths were observed among vaccinated patients.
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