ArticleEvolutionary applications2014
Climate change and habitat fragmentation drive the occurrence of Borrelia burgdorferi, the agent of Lyme disease, at the northeastern limit of its distribution.
Article in Evolutionary applications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 156 citations in OpenAlex.
- A systematic review of the effectiveness and utility of Lyme disease prevention measures in Canada, the United States, and Europe.BMC infectious diseases · 2025Pooled it
- Pooled it
- An updated meta-analysis of the distribution and prevalence of Borrelia burgdorferi s.l. in ticks in Europe.International journal of health geographics · 2018Pooled it
- Projecting lyme disease risk in the United States: A machine learning approach integrating environmental, socioeconomic and vector factors.One health (Amsterdam, Netherlands) · 2025Article
- Article
- Historical Summary of Tick and Animal Surveillance Studies for Lyme Disease in Canada, 1975-2023: A Scoping Review.Zoonoses and public health · 2025Article
- Effects of Peromyscus spp. (Rodentia: Cricetidae) presence, land use, and ecotone on Ixodes scapularis (Acari: Ixodidae) ecology in an emergent area for tick-borne disease.Journal of medical entomology · 2024Article
- Article
- Spatiotemporal trends and covariates of Lyme borreliosis incidence in Poland, 2010-2019.Scientific reports · 2024Article
- Models and data used to predict the abundance and distribution ofLancet regional health. Americas · 2024Article
- High-resolution environmental and host-related factors impacting questingEcology and evolution · 2024Article
- Direct Detection of Lyme Borrelia: Recent Advancement and Use of Aptamer Technology.Biomedicines · 2023Review
- No evidence for direct thermal carryover effects on starvation tolerance in the obligate blood-feeder,Ecology and evolution · 2023Article
- Current and future burden from Lyme disease in Québec as a result of climate change.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023Article
- It's about time: small mammal communities and Lyme disease emergence.Scientific reports · 2023Article
- Analysis of macerated ticks using Boolean logic gating colorimetric isothermal nucleic acid assays for Lyme Borrelia and Ixodes scapularis ticks.Scientific reports · 2023Article
- Risky business: human-related data is lacking from Lyme disease risk models.Frontiers in public health · 2023Review
- Microbial diversity of ticks and a novel typhus group Rickettsia species (Rickettsiales bacterium Ac37b) in Inner Mongolia, China.Parasite (Paris, France) · 2023Article
- Pathogen presence, prevalence, and diversity inFrontiers in parasitology · 2023Article
- Tick Control in a Connected World: Challenges, Solutions, and Public Policy from a United States Border Perspective.Tropical medicine and infectious disease · 2022Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lyme borreliosis is rapidly emerging in Canada, and climate change is likely a key driver of the northern spread of the disease in North America. We used field and modeling approaches to predict the risk of occurrence of Borrelia burgdorferi, the bacteria causing Lyme disease in North America. We combined climatic and landscape variables to model the current and future (2050) potential distribution of the black-legged tick and the white-footed mouse at the northeastern range limit of Lyme disease and estimated a risk index for B. burgdorferi from these distributions. The risk index was mostly constrained by the distribution of the white-footed mouse, driven by winter climatic conditions. The next factor contributing to the risk index was the distribution of the black-legged tick, estimated from the temperature. Landscape variables such as forest habitat and connectivity contributed little to the risk index. We predict a further northern expansion of B. burgdorferi of approximately 250-500 km by 2050 - a rate of 3.5-11 km per year - and identify areas of rapid rise in the risk of occurrence of B. burgdorferi. Our results will improve understanding of the spread of Lyme disease and inform management strategies at the most northern limit of its distribution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.