ArticleIranian journal of reproductive medicine2014
Effects of date palm pollen (Phoenix dactylifera L.) and Astragalus ovinus on sperm parameters and sex hormones in adult male rats.
Article in Iranian journal of reproductive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 70 citations in OpenAlex.
- The role of date palm pollen in women's health and fertility: A narrative review.International journal of reproductive biomedicine · 2026Review
- Bridging bioactive metabolites ofFrontiers in pharmacology · 2026Review
- Therapeutic Potential ofInternational journal of endocrinology · 2025Article
- "Protective effects of artichoke extract and Bifidobacterium longum on male infertility in diabetic rats".Biochemistry and biophysics reports · 2024Article
- Review
- Effects of Date Palm Pollen Supplementations on The Expression ofInternational journal of fertility & sterility · 2023Article
- Date Palm as Source of Nutraceuticals for Health Promotion: a Review.Current nutrition reports · 2022Review
- The effects ofJournal of traditional and complementary medicine · 2022Article
- Potential bioactivity of Phoenix dactylifera fruits, leaves, and seeds against prostate and pancreatic cancer cells.Frontiers in nutrition · 2022Article
- Therapeutic Potential of Date Palm against Human Infertility: A Review.Metabolites · 2021Review
- Efficacy of Herbal Based Syrup on male sexual experiences: A double-blind randomized clinical trial.Journal of traditional and complementary medicine · 2021Article
- Effect of Date Palm Pollen Supplementation on the Egg Production, Ovarian Follicles Development, Hematological Variables and Hormonal Profile of Laying Hens.Animals : an open access journal from MDPI · 2021Article
- The prophylactic effect of date palm (International journal of reproductive biomedicine · 2020Article
- Morphine andJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- Hepatoprotective effect of Stachys pilifera ethanol extract in carbon tetrachloride-induce hepatotoxicity in rats.Pharmaceutical biology · 2017Article
- ETHNOBOTANICAL SURVEY OFAfrican journal of traditional, complementary, and alternative medicines : AJTCAM · 2017Article
- Protective effects of ethyl pyruvate on sperm quality in cyclophosphamide treated mice.Iranian journal of reproductive medicine · 2015Article
- Anticancer activity ofAvicenna journal of phytomedicineArticle
- Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms.Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDate Palm Pollen (DPP) and Astragalus genus are used in some countries for the treatment of infertility.
objectiveThis study was designed to investigate effects of DPP and Astragalus ovinus (A.Ovinus) on fertility in healthy adult male rats. MATERIALS AND
methodsThirty-six rats were divided into six groups (n=6) including control and five treatment groups. DPP (120, 240 and 360 mg/kg) and A.ovinus (100, 500 mg/ kg) were orally given to the treatment groups. After thirty-five days, blood samples were taken to determine serum levels of FSH, LH, testosterone and estradiol. Weight of testis and epididymis, sperm count, sperm motility, seminiferous tubules diameter (STD), germinal cell layer thickness (GCLT), sertoli, leydig and spermatogonia cells were also evaluated.
resultsDPP at the of 120 and 240 mg/kg doses significantly raised the ratio of testis or epididymis to body weight, sperm count, sperm motility , and estradiol level compared to the control group (p<0.05). LH and testosterone levels only noticeably increased at 120 mg/kg of DPP (p<0.01 and p<0.001 respectively). STD increased in the three applied doses (p=0.001). A. ovinus extract at the indicated doses produced a significant reduction in the ratio of testis or epididymis to body weight and sperm motility (p<0.05). Sperm count, spermatogonia, leydig cells and FSH level decreased at dose of 500 mg/kg. Furthermore, GCLT, spermatogonia cells, and serum estradiol level increased at 100 mg/kg dose of A. ovinus.
conclusionOur findings indicate that DPP could improve fertility factors, while A.ovinus can exhibit deleterious effects on gonad and sperm parameters in rats.
Indexed as
Identifiers
25469129PMC4248157W1448436418What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.