Evidence map›Paper›PMID 25469096›Full record

ArticleKorean journal of radiology

Evaluation of aqueductal patency in patients with hydrocephalus: three-dimensional high-sampling-efficiency technique (SPACE) versus two-dimensional turbo spin echo at 3 Tesla.

Murat Ucar, Melike Guryildirim, Nil Tokgoz, Koray Kilic, Alp Borcek, Yusuf Oner, Koray Akkan, Turgut Tali

Abstract readComparative Study
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Novel concepts in the pathogenesis of hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Murat UcarDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.
Melike GuryildirimDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.
Nil TokgozDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.
Koray KilicDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.
Alp BorcekDepartment of Neurosurgery, School of Medicine, Gazi University, Ankara 06510, Turkey.
Yusuf OnerDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.
Koray AkkanDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.
Turgut TaliDepartment of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the accuracy of diagnosing aqueductal patency and image quality between high spatial resolution three-dimensional (3D) high-sampling-efficiency technique (sampling perfection with application optimized contrast using different flip angle evolutions [SPACE]) and T2-weighted (T2W) two-dimensional (2D) turbo spin echo (TSE) at 3-T in patients with hydrocephalus. MATERIALS AND

methodsThis retrospective study included 99 patients diagnosed with hydrocephalus. T2W 3D-SPACE was added to the routine sequences which consisted of T2W 2D-TSE, 3D-constructive interference steady state (CISS), and cine phase-contrast MRI (PC-MRI). Two radiologists evaluated independently the patency of cerebral aqueduct and image quality on the T2W 2D-TSE and T2W 3D-SPACE. PC-MRI and 3D-CISS were used as the reference for aqueductal patency and image quality, respectively. Inter-observer agreement was calculated using kappa statistics.

resultsThe evaluation of the aqueductal patency by T2W 3D-SPACE and T2W 2D-TSE were in agreement with PC-MRI in 100% (99/99; sensitivity, 100% [83/83]; specificity, 100% [16/16]) and 83.8% (83/99; sensitivity, 100% [67/83]; specificity, 100% [16/16]), respectively (p < 0.001). No significant difference in image quality between T2W 2D-TSE and T2W 3D-SPACE (p = 0.056) occurred. The kappa values for inter-observer agreement were 0.714 for T2W 2D-TSE and 0.899 for T2W 3D-SPACE.

conclusionThree-dimensional-SPACE is superior to 2D-TSE for the evaluation of aqueductal patency in hydrocephalus. T2W 3D-SPACE may hold promise as a highly accurate alternative treatment to PC-MRI for the physiological and morphological evaluation of aqueductal patency.

Indexed as

AdolescentAdultAgedChildFemaleHumansHydrocephalusImaging, Three-DimensionalMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedRadiographyRetrospective StudiesSensitivity and SpecificityYoung Adult3D-SPACEAqueductal patencyCerebrospinal fluid flowHydrocephalusMRI

Identifiers

PMID25469096
PMCPMC4248640

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.