Evidence map›Paper›PMID 25469067›Full record

ArticleJournal of Korean medical science2014

Clinical characteristics and survival of Korean idiopathic pulmonary arterial hypertension patients based on vasoreactivity.

Jee Hwan Ahn, Byung Ju Kang, Sun In Hong, Jung Su Lee, Jae Seung Lee, Yeon-Mok Oh, Sang-Do Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Current status of pulmonary arterial hypertension in Korea.The Korean journal of internal medicine · 2019
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jee Hwan AhnDepartment of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0001-6653-998X
Byung Ju KangDepartment of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-1396-7398
Sun In HongDepartment of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0003-2575-2084
Jung Su LeeDepartment of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0001-5644-0150
Jae Seung LeeDepartment of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. ; Center for Pulmonary Hypertension and Venous Thromboembolism, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0003-4130-1486
Yeon-Mok OhDepartment of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0003-0116-4683
Sang-Do LeeDepartment of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. ; Center for Pulmonary Hypertension and Venous Thromboembolism, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0001-8189-4509

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to identify a vasoreactive subset of patients with idiopathic pulmonary arterial hypertension (IPAH) in Korea and to show their clinical characteristics and prognosis. Data on patients who were diagnosed with IPAH at Asan Medical Center between January 1994 and March 2013 were retrospectively collected. Acute vasodilator testing was performed with inhaled nitric oxide during diagnostic right heart catheterization. A positive acute response was defined as a reduction in mean pulmonary arterial pressure (PAP) ≥10 mmHg to an absolute level of mean PAP <40 mmHg without a decrease in cardiac output. Among a total of 60 IPAH patients included for analysis, 9 (15%) showed a positive acute response to acute vasodilator testing. Acute responders showed significantly lower peak velocity of a tricuspid regurgitation jet on echocardiography (4.1±0.3 m/s vs. 4.6±0.6 m/s; P=0.01) and significantly lower mean PAP hemodynamically (47±10 mmHg vs. 63±17 mmHg; P=0.003) than non-responders at baseline. The survival rate of acute responders was 88% at 1, 3, 5, and 10 yr, respectively, which was significantly higher than that of non-responders (85%, 71%, 55%, and 40%, respectively; P=0.029). In conclusion, Korean IPAH patients with vasoreactivity showed better baseline hemodynamic features and survival than those without vasoreactivity.

Indexed as

Vasodilator AgentsAdolescentAdultAgedFemaleHumansHypertension, PulmonaryMaleMiddle AgedPrevalencePrognosisReproducibility of ResultsRepublic of KoreaRisk FactorsSensitivity and SpecificitySurvival RateVasodilator AgentsCalcium Channel BlockersHypertension, PulmonarySurvival RateVasodilator Agents

Identifiers

PMID25469067
PMCPMC4248588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.