ArticleWorld journal of gastroenterology2014
Drug induced acute pancreatitis: does it exist?
Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Methods for the early detection of drug-induced pancreatitis: a systematic review of the literature.BMJ open · 2019Pooled it
- A Case of Thiazide-Induced Pancreatitis.Cureus · 2025Article
- Drug-Induced Pancreatitis Caused by Mesalazine in an Adolescent Man With Ulcerative Colitis: A Case Report.Cureus · 2025Article
- Rare Case of Tacrolimus-Induced Acute Pancreatitis in a Liver Transplant Recipient.ACG case reports journal · 2025Article
- Assessment of pancreatitis associated with tocilizumab use using the United States Food and Drug Administration Adverse Event Reporting System database.Scientific reports · 2021Article
- Acute pancreatitis induced by combination chemotherapy used for the treatment of acute myeloid leukemia: A case report.Medicine · 2020Article
- Successful clozapine rechallenge following recurrent clozapine-associated pancreatitis: a case report.BMC pharmacology & toxicology · 2020Article
- Epidural Steroid Injection-Induced Pancreatitis: A Case Report.The American journal of case reports · 2020Article
- A Drug-Induced Acute Pancreatitis Retrospective Study.Canadian journal of gastroenterology & hepatology · 2020Article
- A case report: acute pancreatitis associated with tacrolimus in kidney transplantation.BMC nephrology · 2019Article
- Pancreatitis: TIGAR-O Version 2 Risk/Etiology Checklist With Topic Reviews, Updates, and Use Primers.Clinical and translational gastroenterology · 2019Review
- Etanercept - A culprit agent in acute pancreatitis?Journal of community hospital internal medicine perspectives · 2019Article
- Acute pancreatitis associated with intravenous administration of propofol: evaluation of causality in a systematic review of the literature.Gastroenterology report · 2019Review
- Acute Pancreatitis after Colonoscopy: A Case Presentation and Literature Review.Case reports in gastrointestinal medicine · 2019Article
- Acetaminophen-induced acute pancreatitis: A case report and literature review.World journal of clinical cases · 2018Article
- Oral metronidazole use and risk of acute pancreatitis: a population-based case-control study.Clinical epidemiology · 2018Article
- Review
- Article
- Albiglutide-induced pancreatitis.Therapeutic advances in drug safety · 2016Article
- Revisiting the reported signal of acute pancreatitis with rasburicase: an object lesson in pharmacovigilance.Therapeutic advances in drug safety · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When confronted with a patient with acute pancreatitis and no clear etiology defined as an absence alcoholism, gallstones (ultrasound and/or MRI), a normal triglyceride level, and absence of tumor, it often appears reasonable to consider a drug as the cause of acute pancreatitis. Over 100 drugs have been implicated by case reports as causing acute pancreatitis. While some of these case reports are well written, many case reports represent poorly written experiences of the clinician simply implicating a drug without a careful evaluation. Over-reliance on case reports while ignoring randomized clinical trials and large pharmacoepidemiologic surveys has led to confusion about drug induced acute pancreatitis. This review will explain that drug induced acute pancreatitis does occur, but it is rare, and over diagnosis leads to misconceptions about the disease resulting in inappropriate patient care, increased litigation and a failure to address the true entity: idiopathic acute pancreatitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.