ReviewWorld journal of gastroenterology2014
Causes and consequences of microsatellite instability in gastric carcinogenesis.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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Who cites it
47 citing papers in PubMed, 80 citations in OpenAlex.
- Advances inOncology letters · 2026Review
- Microsatellite status and its correlation with clinicopathological features in gastric carcinoma: insights from a retrospective study in Northern Pretoria.Pathology oncology research : POR · 2026Article
- Therapeutic Targeting of Oxidative Phosphorylation in Microsatellite Instability-High Gastric Cancer.Journal of Cancer · 2026Article
- Deficient Mismatch Repair and Microsatellite Instability in Solid Tumors.International journal of molecular sciences · 2025Review
- A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer.Oncology reviews · 2025Review
- Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities.Genome medicine · 2024Article
- Review
- Current therapies and progress in the treatment of advanced gastric cancer.Frontiers in oncology · 2024Review
- Article
- Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers.JAMA network open · 2023Article
- Current molecular biomarkers evaluation in gastric/gastroesophageal junction adenocarcinoma: pathologist does matter.Updates in surgery · 2023Article
- Epigenetic reprogramming in cancer: From diagnosis to treatment.Frontiers in cell and developmental biology · 2023Review
- Immune regulation in gastric adenocarcinoma is linked with therapeutic efficacy and improved recovery.Frontiers in genetics · 2023Review
- Clinical outcomes of metachronous recurrence of gastric epithelial neoplasia based on Helicobacter pylori infection status and microsatellite stability.The Korean journal of internal medicine · 2022Article
- Review
- The Emerging Roles of Autophagy in Human Diseases.Biomedicines · 2021Review
- Review
- A greater lymph node yield is required during pathological examination in microsatellite instability-high gastric cancer.BMC cancer · 2021Article
- Recent Advances in the Diagnosis, Staging, Treatment, and Prognosis of Advanced Gastric Cancer: A Literature Review.Frontiers in medicine · 2021Review
- Clinical characteristics and prognostic significance of TCGA and ACRG classification in gastric cancer among the Chinese population.Molecular medicine reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loss of DNA mismatch repair (MMR) function, due to somatic or germline epi/genetic alterations of MMR genes leads to the accumulation of numerous mutations across the genome, creating a molecular phenotype known as microsatellite instability (MSI). In gastric cancer (GC), MSI occurs in about 15% to 30% of the cases. This review summarizes the current knowledge on the molecular mechanisms underlying the acquisition of MSI in GC as well as on the clinic, pathologic and molecular consequences of the MSI phenotype. Additionally, current therapeutic strategies for GC and their applicability in the MSI subset are also discussed.
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