ArticleJournal of biomechanics2015
Subject-specific planning of femoroplasty: an experimental verification study.
Article in Journal of biomechanics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- How accurately do finite element models predict the fall impact response of ex vivo specimens augmented by prophylactic intramedullary nailing?Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- The minimally invasive surgical local osteo-enhancement procedure (LOEP) to deliver a resorbable, tri-phasic calcium-based implant material to address bone loss and strengthen the proximal femur.Frontiers in surgery · 2025Article
- A Surgical Robotic System for Osteoporotic Hip Augmentation: System Development and Experimental Evaluation.IEEE transactions on medical robotics and bionics · 2023Article
- The efficacy of femoral augmentation for hip fracture prevention using ceramic-based cements: A preliminary experimentally-driven finite element investigation.Frontiers in bioengineering and biotechnology · 2023Article
- Mechanical Analysis after Proximal Femoral Reinforcement with Polymethylmethacrylate in Alternated Double Holes.Revista brasileira de ortopedia · 2021Article
- A biomechanically-guided planning and execution paradigm for osteoporotic hip augmentation: Experimental evaluation of the biomechanics and temperature-rise.Clinical biomechanics (Bristol, Avon) · 2021Article
- Fiducial-Free 2D/3D Registration for Robot-Assisted Femoroplasty.IEEE transactions on medical robotics and bionics · 2020Article
- Finite element models for fracture prevention in patients with metastatic bone disease. A literature review.Bone reports · 2020Review
- Treatment of bone loss in proximal femurs of postmenopausal osteoporotic women with AGN1 local osteo-enhancement procedure (LOEP) increases hip bone mineral density and hip strength: a long-term prospective cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- Significance of preoperative planning for prophylactic augmentation of osteoporotic hip: A computational modeling study.Journal of biomechanics · 2019Article
- Biomechanical Test after Hip Cannulated Screw Removal (in vitro Analysis).Revista brasileira de ortopedia · 2019Article
- Article
- A BIOMECHANICAL AND THERMAL ANALYSIS FOR BONE AUGMENTATION OF THE PROXIMAL FEMUR.International Mechanical Engineering Congress and Exposition : [proceedings]. International Mechanical Engineering Congress and Exposition · 2018Article
- PRELIMINARY MECHANICAL TEST OF PROXIMAL FEMUR REINFORCEMENT WITH CEMENTED X-SHAPED PMMA.Acta ortopedica brasileira · 2018Article
- Discrete particle model for cement infiltration within open-cell structures: Prevention of osteoporotic fracture.PloS one · 2018Article
- Static bending test after proximal femoral nail (PFN) removal -Revista brasileira de ortopedia · 2017Article
- Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture.Archives of osteoporosis · 2016Review
- Prophylactic augmentation of the osteoporotic proximal femur-mission impossible?BoneKEy reports · 2016Review
- EVALUATION OF A BONE REINFORCEMENT TECHNIQUE USING FINITE ELEMENT ANALYSIS.Acta ortopedica brasileiraArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The risk of osteoporotic hip fractures may be reduced by augmenting susceptible femora with acrylic polymethylmethacrylate (PMMA) bone cement. Grossly filling the proximal femur with PMMA has shown promise, but the augmented bones can suffer from thermal necrosis or cement leakage, among other side effects. We hypothesized that, using subject-specific planning and computer-assisted augmentation, we can minimize cement volume while increasing bone strength and reducing the risk of fracture. We mechanically tested eight pairs of osteoporotic femora, after augmenting one from each pair following patient-specific planning reported earlier, which optimized cement distribution and strength increase. An average of 9.5(±1.7) ml of cement was injected in the augmented set. Augmentation significantly (P<0.05) increased the yield load by 33%, maximum load by 30%, yield energy by 118%, and maximum energy by 94% relative to the non-augmented controls. Also predicted yield loads correlated well (R(2)=0.74) with the experiments and, for augmented specimens, cement profiles were predicted with an average surface error of <2 mm, further validating our simulation techniques. Results of the current study suggest that subject-specific planning of femoroplasty reduces the risk of hip fracture while minimizing the amount of cement required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.