Evidence map›Paper›PMID 25468608›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2015

Avians as a model system of vascular development.

Michael Bressan, Takashi Mikawa

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The avian embryo as a time-honoured animal model in developmental, biomedical and agricultural research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael BressanCardiovascular Research Institute, University of California, San Francisco, 555 Mission Bay Blvd South, MC3120, San Francisco, CA, 94143-3120, USA, michael.bressan@ucsf.edu.
Takashi Mikawa

Funding

Coronary Vascular Cell DevelopmentR37HL078921 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIKAWA, TAKASHI · 2010 to 2019
$3.8M
Cardiac Conduction System DevelopmentR01HL093566 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIKAWA, TAKASHI · 2008 to 2012
$2.0M
Cardiac Pacemaker DevelopmentR01HL112268 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIKAWA, TAKASHI · 2012 to 2016
$1.9M
INDUCTION OF CORONARY ENDOTHELIAL CELL LINEAGER01HL078921 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI MIKAWA, TAKASHI · 2005 to 2009
$1.9M
Heart Field DevelopmentR01HL122375 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIKAWA, TAKASHI · 2014 to 2017
$1.6M
Vascular Differentiation and PatterningR01HL092429 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIKAWA, TAKASHI · 2009 to 2012
$1.5M
Developmental Patterning of the Sinoatrial NodeR00HL122360 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRESSAN, MICHAEL C · 2016 to 2018
$745k
Developmental Patterning of the Sinoatrial NodeK99HL122360 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BRESSAN, MICHAEL C · 2014 to 2015
$190k
NHLBI NIH HHS 1K99HL122360-01NHLBI NIH HHS HL078921NHLBI NIH HHS HL092429NHLBI NIH HHS HL093566NHLBI NIH HHS HL112268NHLBI NIH HHS HL122375NHLBI NIH HHS K99 HL122360NHLBI NIH HHS R00 HL122360NHLBI NIH HHS R01 HL078921NHLBI NIH HHS R01 HL092429NHLBI NIH HHS R01 HL093566NHLBI NIH HHS R01 HL112268NHLBI NIH HHS R01 HL122375NHLBI NIH HHS R37 HL078921
6 · The paper itself

Abstract

For more than 2,000 years, philosophers and scientists have turned to the avian embryo with questions of how life begins (Aristotle and Peck Generations of Animals. Loeb Classics, vol. XIII. Harvard University Press, Cambridge, 1943; Needham, A history of embryology. Abelard-Schuman, New York, 1959). Then, as now, the unique accessibility of the embryo both in terms of acquisition of eggs from domesticated fowl and ease at which the embryo can be visualized by simply opening the shell has made avians an appealing and powerful model system for the study of development. Thus, as the field of embryology has evolved through observational, comparative, and experimental embryology into its current iteration as the cellular and molecular biology of development, avians have remained a useful and practical system of study.

Indexed as

Models, AnimalAblation TechniquesAnimalsBlood VesselsCell TransplantationChick EmbryoChickensChorioallantoic MembraneCoturnixEmbryologyGene Transfer TechniquesGenomicsHybridization, GeneticStaining and LabelingTissue Culture Techniques

Identifiers

PMID25468608
PMCPMC4582444

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.