Evidence map›Paper›PMID 25468504›Full record

ArticleBMJ open2014

Spatial variation of heart failure and air pollution in Warwickshire, UK: an investigation of small scale variation at the ward-level.

Oscar Bennett, Ngianga-Bakwin Kandala, Chen Ji, John Linnane, Aileen Clarke

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Chronic Benzene Exposure Aggravates Pressure Overload-Induced Cardiac Dysfunction.Toxicological sciences : an official journal of the Society of Toxicology · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oscar BennettPublic Health Warwickshire, Communities Group, Warwickshire County Council, Warwick, UK.ORCID http://orcid.org/0000-0003-4546-1807
Ngianga-Bakwin KandalaDivision of Health Sciences, University of Warwick Medical School, Coventry, UK Division of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Johannesburg, South Africa.
Chen JiDivision of Health Sciences, University of Warwick Medical School, Coventry, UK.
John LinnanePublic Health Warwickshire, Communities Group, Warwickshire County Council, Warwick, UK.
Aileen ClarkeDivision of Health Sciences, University of Warwick Medical School, Coventry, UK.

Funding

Department of Health WMCLAHRC-2014-1
6 · The paper itself

Abstract

objectivesTo map using geospatial modelling techniques the morbidity and mortality caused by heart failure within Warwickshire to characterise and quantify any influence of air pollution on these risks.

designCross-sectional.

settingWarwickshire, UK.

participantsData from all of the 105 current Warwickshire County wards were collected on hospital admissions and deaths due to heart failure.

resultsIn multivariate analyses, the presence of higher mono-nitrogen oxide (NOx) in a ward (3.35:1.89, 4.99), benzene (Ben) (31.9:8.36, 55.85) and index of multiple deprivation (IMD; 0.02: 0.01, 0.03), were consistently associated with a higher risk of heart failure morbidity. Particulate matter (Pm; -12.93: -20.41, -6.54) was negatively associated with the risk of heart failure morbidity. No association was found between sulfur dioxide (SO2) and heart failure morbidity. The risk of heart failure mortality was higher in wards with a higher NOx (4.30: 1.68, 7.37) and wards with more inhabitants 50+ years old (1.60: 0.47, 2.92). Pm was negatively associated (-14.69: -23.46, -6.50) with heart failure mortality. SO2, Ben and IMD scores were not associated with heart failure mortality. There was a prominent variation in heart failure morbidity and mortality risk across wards, the highest risk being in the regions around Nuneaton and Bedworth.

conclusionsThis study showed distinct spatial patterns in heart failure morbidity and mortality, suggesting the potential role of environmental factors beyond individual-level risk factors. Air pollution levels should therefore be taken into account when considering the wider determinants of public health and the impact that changes in air pollution might have on the health of a population.

Indexed as

Public HealthAir PollutionCross-Sectional StudiesHeart FailureHumansMorbidityPatient AdmissionPatients' RoomsRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateUnited KingdomEPIDEMIOLOGYSOCIAL MEDICINE

Identifiers

PMID25468504
PMCPMC4256640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.