ArticleHealth and quality of life outcomes2014
The impact of neuropathic pain and other comorbidities on the quality of life in patients with diabetes.
Article in Health and quality of life outcomes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05670600 (The Effect of Foot and Ankle Exercise on Pain and Quality of Life in Patients With Diabetic Neuropathy), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Foot and Ankle Exercise on Pain and Quality of Life in Patients With Diabetic Neuropathy
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Exercise and Neuropathy: Systematic Review with Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Quality of Life in Painful Peripheral Neuropathies: A Systematic Review.Pain research & management · 2019Pooled it
- Effects of Vascular Photobiomodulation on Glycemic Control in Patients With Type II Diabetes Mellitus: A Prospective Single-Arm Clinical Study.Lasers in surgery and medicine · 2026Trial
- Efficacy of recurrent transcutaneous magnetic stimulation in the treatment of diabetic peripheral neuropathy: Multicenter randomized trial.Pain practice : the official journal of World Institute of Pain · 2023Trial
- Neuropathy symptom and change: Inotersen treatment of hereditary transthyretin amyloidosis.Muscle & nerve · 2020Trial
- A multimodal manual therapy, exercise, and psychological intervention for painful diabetic neuropathy: the NeuOst feasibility randomised controlled trial.Pain reports · 2026Article
- Relationship between Postoperative Neuropathic Pain and Clinical Scores in Patients with Cervical Ossification of the Posterior Longitudinal Ligament.Spine surgery and related research · 2026Article
- Metabolic and neuropathic outcomes following combined sodium-glucose cotransporter-2 inhibitor therapy and adjunctive acupuncture in obese patients with diabetic neuropathy: a case series.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study.Future science OA · 2025Article
- Calcium Channel αPain and therapy · 2025Review
- Comparative Efficacy and Safety of Two Different Formulations of Linear Hyaluronic Acid in Patients with Knee Osteoarthritis.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Cost-of-illness study among patients with diabetes mellitus and coping mechanisms in Northern Ghana.BMJ public health · 2025Article
- Assessing Gender Differences in Neuropathic Pain Management: Findings from a Real-Life Clinical Cross-Sectional Observational Study.Journal of clinical medicine · 2024Article
- Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain.International journal of molecular sciences · 2024Article
- Review
- Biopsychosocial rehabilitation therapy in small fiber neuropathy: research protocol to study the effect of rehabilitation treatment.Frontiers in neurology · 2024Article
- Nerve conduction velocity is independently associated with bone mineral density in type 2 diabetes mellitus.Frontiers in endocrinology · 2023Article
- Soreness or sng: a common symptom with differential clinical impact from pain in degenerative lumbar spine diseases.BMJ open quality · 2023Article
- CHRONIC COMPLICATIONS OF DIABETES AND QUALITY OF LIFE.Acta clinica Croatica · 2022Review
- Analysis of clinical phenotypes of neuropathic symptoms in patients with type 2 diabetes: A multicenter study.Journal of diabetes investigation · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic polyneuropathy (DPN) is one of the most common complications of diabetes and can exist with or without neuropathic pain. We were interested in how neuropathic pain impairs the quality of life in diabetic patients and what is the role of comorbidities in this condition.
methodsThe study included 80 patients with painful DPN (group "P") and 80 patients with DPN, but without neuropathic pain (group "D"). Visual analogue scale (VAS) and Leeds assessment of neuropathic symptoms and signs (LANSS) pain scale were used for assessment of neuropathic pain, SF-36 standardized questionnaire for assessment of the quality of life and BDI questionnaire for assessment of depression.
resultsSubjects in group P had statistically significantly lower values compared to group D in all 8 dimensions and both summary values of the SF-36 scale. We ascribe the extremely low results of all parameters of SF-36 scale in group P to painful diabetic polyneuropathy with its complications. The patients in group D showed higher average values in all dimension compared to group P, but also somewhat higher quality of life compared to general population of Croatia in 4 of 8 dimensions, namely vitality (VT), social functioning (SF), role-emotional (RE) and mental health (MH), which was unexpected result. Clinically, the most pronounced differences between two groups were noted in sleeping disorders and problems regarding micturition and defecation , which were significantly more expressed in group P. The similar situation was with walking distance and color-doppler sonography of carotid arteries, which were significantly worse in group P. Consequently, subjects in group P were more medicated than the patients in group D, particularly with tramadol, antiepileptics and antidepressants.
conclusionPainful DPN is a major factor that influences various aspects of quality of life in diabetic patients. Additionally, this study gives an overview of diabetic population in the Republic of Croatia, information that could prove useful in future studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.