Evidence map›Paper›PMID 25468158›Full record

ArticleLancet (London, England)2015

Health, functioning, and disability in older adults--present status and future implications.

Somnath Chatterji, Julie Byles, David Cutler, Teresa Seeman, Emese Verdes

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Lancet (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07180147 (Arlington Longitudinal Optimal Healthy Aging Study), which is not on this map. Cited by 439 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
439citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07180147 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

TypeobservationalSponsorMarymount UniversityRan2025 to 2031Enrolled500ConditionsAlzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome
3 · Its place in the literature

Who cites it

439 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  12. Cross-national comparison of the association between adult child educational attainment and older parents' functional health.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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  17. Does long-term care insurance affect labor supply? Empirical evidence from China.International journal of health economics and management · 2026
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379 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

5 authors.

Somnath ChatterjiSurveys, Measurement, and Analysis, Health Statistics and Information Systems, WHO, Geneva, Switzerland. Electronic address: chatterjis@who.int.
Julie BylesResearch Centre for Gender Health and Ageing, University of Newcastle, Callaghan, NSW, Australia.
David CutlerDepartment of Economics and Kennedy School of Government, Harvard University, Cambridge MA, USA.
Teresa SeemanDivision of Geriatrics, David Geffen School of Medicine at University of California, Los Angeles CA, USA.
Emese VerdesSurveys, Measurement, and Analysis, Health Statistics and Information Systems, WHO, Geneva, Switzerland.

Funding

Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI Katherine Baicker · 1986 to 2026
$56.5M
Towards improving the measurement of health and disability trends, the compressioR01AG034479 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH · 2010 to 2014
$5.3M
Harmonizing health outcomes and determinants across longitudinal studies on agingR21AG034263 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH, KOWAL, PAUL R. · 2011 to 2012
$255k
NCI NIH HHS YA1323-08-CN-0020NIA NIH HHS P01 AG005842NIA NIH HHS R01 AG034479NIA NIH HHS R01-AG034479NIA NIH HHS R21 AG034263NIA NIH HHS R21-AG034263NIA NIH HHS Y1-AG- 1005-01PHS HHS OGHA 04034785World Health Organization 001
6 · The paper itself

Abstract

Ageing is a dynamic process, and trends in the health status of older adults aged at least 60 years vary over time because of several factors. We examined reported trends in morbidity and mortality in older adults during the past two decades to identify patterns of ageing across the world. We showed some evidence for compression of morbidity (ie, a reduced amount of time spent in worse health), in four types of studies: 1) of good quality based on assessment criteria scores; 2) those in which a disability-related or impairment-related measure of morbidity was used; 3) longitudinal studies; or 4) studies undertaken in the USA and other high-income countries. Many studies, however, reported contrasting evidence (ie, for an expansion of morbidity), but with different methods, these measures are not directly comparable. Expansion of morbidity was more common when trends in chronic disease prevalence were studied. Our secondary analysis of data from longitudinal ageing surveys presents similar results. However, patterns of limitations in functioning vary substantially between countries and within countries over time, with no discernible explanation. Data from low-income countries are very sparse, and efforts to obtain information about the health of older adults in less-developed regions of the world are urgently needed. We especially need studies that focus on refining measurements of health, functioning, and disability in older people, with a core set of domains of functioning, that investigate the effects of these evolving patterns on the health-care system and their economic implications.

Indexed as

Activities of Daily LivingDeveloped CountriesDeveloping CountriesHealth StatusLife ExpectancyMorbidityAgedHumansMiddle Aged

Identifiers

PMID25468158
PMCPMC4882096

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.