ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2015
HIV infection and arterial inflammation assessed by (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET): a prospective cross-sectional study.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Association between Immune Markers and Surrogate Markers of Cardiovascular Disease in HIV Positive Patients: A Systematic Review.PloS one · 2017Pooled it
- Rationale, design, and baseline characteristicss of the effect of PCSK9 inhibition on cardiovascular risk in treated HIV infection: EPIC-HIV randomized clinical trial.American heart journal · 2026Trial
- Evolving mechanisms and presentations of cardiovascular disease in people with HIV: implications for management.Clinical microbiology reviews · 2024Review
- Coronary Artery Disease in Persons With Human Immunodeficiency Virus Without Detectable Viral Replication.Open forum infectious diseases · 2023Article
- Investigating vascular diseases in people living with HIV by nuclear imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Pattern of arterial inflammation and inflammatory markers in people living with HIV compared with uninfected people.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Impact of optimized PET imaging conditions onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- [Biomolecules · 2020Article
- Arterial inflammation in young patients with human immunodeficiency virus infection: A cross-sectional study using F-18 FDG PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Subclinical Atherosclerosis Imaging in People Living with HIV.Journal of clinical medicine · 2019Review
- Radionuclide imaging of inflammation in atherosclerotic vascular disease among people living with HIV infection: current practice and future perspective.European journal of hybrid imaging · 2019Review
- HIV and Cardiovascular Disease: Update on Clinical Events, Special Populations, and Novel Biomarkers.Current HIV/AIDS reports · 2018Review
- The effects of HIV and smoking on aortic and splenic inflammation.AIDS (London, England) · 2018Article
- HIV Infection and Risk of Cardiovascular Diseases Beyond Coronary Artery Disease.Current atherosclerosis reports · 2017Review
- Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection.JAMA cardiology · 2017Observational
- Review of cardiovascular imaging in the journal of nuclear cardiology in 2015. Part 1 of 2: Plaque imaging, positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
- Observational
- (18)F-FDG PET imaging in detection of radiation-induced vascular disease in lymphoma survivors.American journal of nuclear medicine and molecular imaging · 2015Article
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Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHIV-infected patients are at increased risk of myocardial infarction and arterial inflammation has been suggested as a pathophysiological explanation. We compared the uptake of (18)F-fluorodeoxyglucose (FDG) by PET in four arterial regions, and factors associated with FDG uptake in well-treated HIV-infected patients without cardiovascular disease (CVD) and healthy controls. METHODS AND
resultsWe prospectively scanned 26 HIV-infected patients on stable antiretroviral therapy and 25 healthy volunteers with FDG PET/CT, measuring standardized uptake values (SUV) in the carotid arteries, the ascending, descending, and abdominal aorta. We performed correlation analyses between FDG uptake and intima-media thickness (IMT), and soluble biomarkers of inflammation. We found no difference in arterial FDG uptake between the HIV-infected patients and healthy controls quantified either as mean SUVmax or target-to background ratio in the carotid region, the ascending aorta, the descending aorta, or the abdominal aorta. Correlations between SUV, IMT, and soluble biomarkers were scarce in both groups.
conclusionIn a group of optimally treated HIV-infected patients with full viral suppression, low Framingham risk score and no known CVD, we found no evidence of increased arterial inflammation as assessed by FDG PET/CT compared to healthy volunteers.
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