Evidence map›Paper›PMID 25467187›Full record

Observational studyBMC pregnancy and childbirth2014

Linkage to HIV care, postpartum depression, and HIV-related stigma in newly diagnosed pregnant women living with HIV in Kenya: a longitudinal observational study.

Bulent Turan, Kristi L Stringer, Maricianah Onono, Elizabeth A Bukusi, Sheri D Weiser, Craig R Cohen, Janet M Turan

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC pregnancy and childbirth, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07064928 (We Are Together), which is not on this map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07064928 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

We Are Together (WAT): Development and Testing of an Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2027Enrolled175ConditionsHIV, HIV - Human Immunodeficiency Virus, Postpartum, PregnancyArmsAdapted Project Accept's Post-Test Support Services (PTSS) Module 3
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Bulent TuranDepartment of Psychology, University of Alabama at Birmingham, CH 415, 1530 3rd Avenue South, Birmingham, AL, 35294-1170, USA. bturanb@gmail.com.
Kristi L StringerDepartment of Sociology, University of Alabama at Birmingham, HHB 460, 1720 2nd Ave South, Birmingham, AL, 35294-1152, USA. Kls5n@uab.edu.
Maricianah OnonoCentre for Microbiology Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya. maricianah@yahoo.com.
Elizabeth A BukusiCentre for Microbiology Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya. ebukusi@rctp.or.ke.
Sheri D WeiserDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA. Sheri.Weiser@ucsf.edu.
Craig R CohenDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA. CCohen@globalhealth.ucsf.edu.
Janet M TuranDepartment of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA. jmturan@uab.edu.
University of Alabama at Birmingham · USKenya Medical Research Institute · KEUniversity of California, San Francisco · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
UAB Health Services Research (HSR) Training ProgramT32HS013852 · AHRQ · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEVITAN, EMILY B, MUGAVERO, MICHAEL J · 2003 to 2024
$8.0M
The Effects of HIV/AIDS Stigma on Use of Services by Pregnant Women in KenyaK01MH081777 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TURAN, JANET M. · 2007 to 2011
$842k
Substance Abuse Stigma and Engagement in HIV Care: A Mixed Methods InvestigationF31DA037106 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STRINGER, KRISTI LYNN · 2014 to 2017
$116k
AHRQ HHS 2 T32 HS013852AHRQ HHS T32 HS013852NIDA NIH HHS F31 DA037106NIDA NIH HHS F31DA037106NIMH NIH HHS K01 MH081777NIMH NIH HHS K01MH081777NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

backgroundWhile studies have suggested that depression and HIV-related stigma may impede access to care, a growing body of literature also suggests that access to HIV care itself may help to decrease internalized HIV-related stigma and symptoms of depression in the general population of persons living with HIV. However, this has not been investigated in postpartum women living with HIV. Furthermore, linkage to care itself may have additional impacts on postpartum depression beyond the effects of antiretroviral therapy. We examined associations between linkage to HIV care, postpartum depression, and internalized stigma in a population with a high risk of depression: newly diagnosed HIV-positive pregnant women.

methodsIn this prospective observational study, data were obtained from 135 HIV-positive women from eight antenatal clinics in the rural Nyanza Province of Kenya at their first antenatal visit (prior to testing HIV-positive for the first time) and subsequently at 6 weeks after giving birth.

resultsAt 6 weeks postpartum, women who had not linked to HIV care after testing positive at their first antenatal visit had higher levels of depression and internalized stigma, compared to women who had linked to care. Internalized stigma mediated the effect of linkage to care on depression. Furthermore, participants who had both linked to HIV care and initiated antiretroviral therapy reported the lowest levels of depressive symptoms.

conclusionsThese results provide further support for current efforts to ensure that women who are newly diagnosed with HIV during pregnancy become linked to HIV care as early as possible, with important benefits for both physical and mental health.

Indexed as

Social StigmaAdolescentAdultAntiretroviral Therapy, Highly ActiveDepression, PostpartumFemaleHIV InfectionsHIV SeropositivityHumansKenyaLongitudinal StudiesMultivariate AnalysisPostpartum PeriodPregnancyPregnancy Complications, InfectiousPregnant People

Identifiers

PMID25467187
PMCPMC4261547
OpenAlexW1974259798

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.