Evidence map›Paper›PMID 25466985›Full record

SynthesisJournal of psychosomatic research2015

The association between depressive symptoms in the community, non-psychiatric hospital admission and hospital outcomes: a systematic review.

A Matthew Prina, Theodore D Cosco, Tom Dening, Aartjan Beekman, Carol Brayne, Martijn Huisman

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of psychosomatic research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A Matthew PrinaDepartment of Public Health & Primary Care, Institute of Public Health, Cambridge University, UK; NIHR Collaboration for Leadership in Applied Health Research & Care for Cambridgeshire & Peterborough (CLAHRC-CP), UK; King's College London, Institute of Psychiatry, Health Service and Population Research Department, Centre for Global Mental Health, London, UK. Electronic address: matthew.prina@kcl.ac.uk.
Theodore D CoscoDepartment of Public Health & Primary Care, Institute of Public Health, Cambridge University, UK.
Tom DeningNIHR Collaboration for Leadership in Applied Health Research & Care for Cambridgeshire & Peterborough (CLAHRC-CP), UK; Division of Psychiatry, Institute of Mental Health, University of Nottingham, UK.
Aartjan BeekmanDepartment of Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.
Carol BrayneDepartment of Public Health & Primary Care, Institute of Public Health, Cambridge University, UK; NIHR Collaboration for Leadership in Applied Health Research & Care for Cambridgeshire & Peterborough (CLAHRC-CP), UK.
Martijn HuismanDepartment of Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands; Department of Sociology, VU University, Amsterdam, The Netherlands.

Funding

Medical Research Council K021907/1Medical Research Council RG56433
6 · The paper itself

Abstract

objectivesThis paper aims to systematically review observational studies that have analysed whether depressive symptoms in the community are associated with higher general hospital admissions, longer hospital stays and increased risk of re-admission.

methodsWe identified prospective studies that looked at depressive symptoms in the community as a risk factor for non-psychiatric general hospital admissions, length of stay or risk of re-admission. The search was carried out on MEDLINE, PsycINFO, Cochrane Library Database, and followed up with contact with authors and scanning of reference lists.

resultsEleven studies fulfilled our inclusion and exclusion criteria, and all were deemed to be of moderate to high quality. Meta-analysis of seven studies with relevant data suggested that depressive symptoms may be a predictor of subsequent admission to a general hospital in unadjusted analyses (RR=1.36, 95% CI: 1.28-1.44), but findings after adjustment for confounding variables were inconsistent. The narrative synthesis also reported depressive symptoms to be independently associated with longer length of stay, and higher re-admission risk.

conclusionsDepressive symptoms are associated with a higher risk of hospitalisation, longer length of stay and a higher re-admission risk. Some of these associations may be mediated by other factors, and should be explored in more details.

Indexed as

Hospitals, GeneralIndependent LivingDatabases, FactualDepressionHospitalizationHumansLength of StayPatient AdmissionPatient ReadmissionRisk FactorsComorbidityDepressionDepressive symptomsHospitalisationLength of stayPatient re-admission

Identifiers

PMID25466985
PMCPMC4292984

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.