ArticleCurrent biology : CB2014
Binding of episodic memories in the rat.
Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 72 citations in OpenAlex.
- Rats replay episodic memories in context.Current biology : CB · 2026Article
- Temporal context-guided memory capabilities in rodents.Scientific reports · 2025Article
- Timing is everything: The effect of early-life seizures on developing neuronal circuits subserving spatial memory.Epilepsia open · 2025Review
- Validation of a rodent model of episodic memory replay.Learning & behavior · 2025Article
- Rats show up to 72 h of significant retention for spatial memory in the radial maze.Learning & behavior · 2024Article
- Mental time travel in the rat.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Is episodic-like memoryPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- The constructive nature of memories in insects: bumblebees as a case study.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- False memories in cuttlefish.iScience · 2024Article
- Review
- Optogenetic modulation of hippocampal oscillations ameliorates spatial cognition and hippocampal dysrhythmia following early-life seizures.Neurobiology of disease · 2023Article
- Memory recall: New behavioral protocols for examining distinct forms of context specific recall in animals.Neurobiology of learning and memory · 2022Article
- Anterior thalamic nuclei: A critical substrate for non-spatial paired-associate memory in rats.The European journal of neuroscience · 2022Article
- Developmental trajectory of episodic-like memory in rats.Frontiers in behavioral neuroscience · 2022Article
- Towards a comparative science of emotion: Affect and consciousness in humans and animals.Neuroscience and biobehavioral reviews · 2020Review
- Biological Sex and Sex Hormone Impacts on Deficits in Episodic-Like Memory in a Rat Model of Early, Pre-motor Stages of Parkinson's Disease.Frontiers in neurology · 2020Article
- Slow Progress with the Most Widely Used Animal Model: Ten Years of Metacognition Research in Rats, 2009-2019.Animal behavior and cognition · 2019Article
- Construction and disruption of spatial memory networks during development.Learning & memory (Cold Spring Harbor, N.Y.) · 2019Review
- The role of context in animal memory.Learning & behavior · 2019Review
- Replay of Episodic Memories in the Rat.Current biology : CB · 2018Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
People remember an event as a coherent scene. Memory of such an episode is thought to reflect binding of a fully integrated representation, rather than memory of unconnected features. However, it is not known whether rodents form bound representations. Here we show that rats remember episodes as bound representations. Rats were presented with multiple features of unique episodes at memory encoding: what (food flavor), where (maze location), source (self-generated food seeking—running to the food site—or experimenter-generated food seeking—placement by the experimenter at the food site), and context (spatial cues in the room where the event occurred). After a delay, the trial continued with a memory assessment in which one flavor replenished at the self-generated—but not at experimenter-generated—locations. We presented rats with multiple overlapping features, in rapid succession, to ensure that successful memory retrieval required them to disambiguate multiple study episodes (using two rooms). We found that binding is resistant to interference from highly similar episodes and survives long retention intervals (∼1 week). Our results suggest that multiple episodic memories are each structured as bound representations, which suggests that nonhumans represent episodic memories using a structure similar to that of people. This finding enhances the translational potential for utilizing animal models of episodic memory to explore the biological mechanisms of memory and validate therapeutic approaches for treating disorders of memory.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.