Trial reportEuropean radiology2015
Ultrasound-guided percutaneous injection to treat de Quervain's disease using three different techniques: a randomized controlled trial.
Trial report in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Management of de Quervain Tenosynovitis: A Systematic Review and Network Meta-Analysis.JAMA network open · 2023Pooled it
- Unblinding de Quervain: A systematic review of ultrasound-guided injection of corticosteroids for treatment of stenosing tenosynovitis of the 1st extensor compartment.Journal of medical radiation sciences · 2023Pooled it
- Can Hyaluronic Acid Reduce Friction in the First Extensor Compartment? A Cadaveric Study.Journal of wrist surgery · 2026Article
- A Scoping Review of Clinical Studies on Procedures of Ultrasound-Guided Injection to Ensure Hygiene and Safety.Healthcare (Basel, Switzerland) · 2025Review
- Comparative Analysis of Ultrasound and Surgical Findings in Anatomical Variations of de Quervain's Disease.Clinics in orthopedic surgery · 2025Article
- Efficacy of Local Intralesional Steroid Injection for Pain Relief in De Quervain's Tenosynovitis.Cureus · 2024Article
- Ultrasound guided procedures in the musculoskeletal system: a narrative review with illustrative examples.Quantitative imaging in medicine and surgery · 2024Review
- Efficacy of Ultrasound-Guided Hydrodissection for Treating De Quervain's Tenosynovitis.JPRAS open · 2024Article
- A Practical Guide to Injection Therapy in Hand Tendinopathies: A Systematic Review of Randomized Controlled Trials.Journal of functional morphology and kinesiology · 2024Review
- Article
- Review
- Tendon injections - upper extremity.Skeletal radiology · 2023Review
- De Quervain's tenosynovitis: a non-randomized two-armed study comparing ultrasound-guided steroid injection with surgical release.Musculoskeletal surgery · 2023Review
- Ultrasound-guided musculoskeletal interventional procedures around the elbow, hand and wrist excluding carpal tunnel procedures.Journal of ultrasonography · 2021Article
- Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)-Part II, elbow and wrist.European radiology · 2020Article
- Ultrasound-guided steroid injection for the treatment of de Quervain's disease: an anatomy-based approach.Skeletal radiology · 2018Article
- Rotator cuff calcific tendinopathy: from diagnosis to treatment.Acta bio-medica : Atenei Parmensis · 2018Review
- In vivo feasibility of real-time MR-US fusion imaging lumbar facet joint injections.Journal of ultrasound · 2017Article
- Ultrasound-guided procedures to treat sport-related muscle injuries.The British journal of radiology · 2016Review
- Ultrasound-guided intervention in the ankle and foot.The British journal of radiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the six-month outcome of three different ultrasound-guided treatments for de Quervain's disease (DQD).
methodsWe prospectively treated 75 consecutive patients (51 females, 24 males, mean age ± standard deviation = 45.3 ± 9.8 years) with DQD. Patients' features (hand dominance, intraretinaculum septum, accessory tendons) were recorded. Visual analogue scale (VAS), reduced disability (quickDASH) score, and retinaculum thickness were evaluated at baseline and after one (excluding retinaculum thickness), three, and six months. Patients were randomized into three groups of 25 patients each treated under ultrasound guidance: Group A (1 ml methylprednisolone acetate; mean baseline thickness = 1.6 mm; mean baseline VAS = 6; mean baseline quickDASH = 55); Group B (1 ml methylprednisolone acetate +15-day delayed 2 ml saline 0.9 %; 1.4; 6; 56); Group C (1 ml methylprednisolone acetate +15-day delayed 2 ml low molecular weight hyaluronic acid; 1.7; 6; 55).
resultsAfter one month results were: Group A mean VAS = 2; mean quickDASH = 23; Group B 2; 22; Group C 2; 21. After three months results were: Group A retinaculum thickness = 0.7 mm; 3; 27); Group B 0.8 mm; 1; 25; Group C 0.5 mm; 1; 23. After six months results were: Group A 1.5 mm; 3; 51; Group B 1 mm; 2; 51; Group C 0.7 mm; 1; 26 (P < 0.001 for all vs. baseline). Patients' age, sex, hand dominance, presence of subcompartment dividing septum, and supernumerary tendons had no influence on outcome (P ≥ 0.177).
conclusionAddition of hyaluronic acid to ultrasound-guided injections of steroids to treat DQD seems to improve the outcome and to reduce the recurrence rate. KEY POINTS: • Ultrasound guidance allows for safe injection procedures to treat de Quervains' disease • Steroid injections allow prompt recovery in de Quervain's disease with short-term recurrence • Addition of hyaluronic acid allows recurrence rate reduction compared to simple steroid injections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.