ArticleBMC plant biology2014
Trihelix transcription factor GT-4 mediates salt tolerance via interaction with TEM2 in Arabidopsis.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 72 citations in OpenAlex.
- The Trihelix Genes inBiomolecules · 2026Article
- GhCOR27 confers Verticillium wilt resistance in cotton by relieving the GhASIL1-GhERF114-mediated repression of lignin accumulation.Plant physiology · 2026Article
- Novel Molecular Markers and Immune-Related Candidate Genes for Blackleg Resistance in Rapeseed: A Genome-Wide Analysis.International journal of molecular sciences · 2026Article
- Trihelix transcription factors: versatile regulators in plant growth and development, abiotic, and biotic stress responses.Plant cell reports · 2026Review
- Genome-Wide Identification and Characterization of the Trihelix Transcription Factor Family inPlants (Basel, Switzerland) · 2025Article
- Genome-wide identification, phylogenetic analysis and expression pattern study of trihelix transcription factors in Pisum sativum L.Scientific reports · 2025Article
- Molecular modelling and gene expression analysis to probe the GT-γ trihelix transcription factors in Solanum tuberosum under drought stress.Scientific reports · 2025Article
- Red peel regulator 1 links ethylene response factor 25 and β-citraurin biosynthetic genes to regulate ethylene-induced peel reddening in citrus.The Plant cell · 2024Article
- Genome-Wide Identification of the Trihelix Transcription Factor Family and Functional Analysis ofInternational journal of molecular sciences · 2024Article
- The melonPlant direct · 2024Article
- Genome-wide expression analysis ofPlant signaling & behavior · 2023Article
- Comprehensive Genomic Analysis of Trihelix Family in Tea Plant (Plants (Basel, Switzerland) · 2023Article
- Genome-wide identification and expression analysis of the trihelix transcription factor family in sesame (Sesamum indicum L.) under abiotic stress.Molecular biology reports · 2023Article
- Genome-wide characterization, evolutionary analysis, and expression pattern analysis of the trihelix transcription factor family and gene expression analysis under MeJA treatment in Panax ginseng.BMC plant biology · 2023Article
- Transcriptome-Wide Integrated Analysis of thePlants (Basel, Switzerland) · 2023Article
- GT Transcription Factors ofBiology · 2023Article
- Article
- Overexpression of the cotton trihelix transcription factorFrontiers in plant science · 2023Article
- Conservation and Divergence of the Trihelix Genes in Brassica and Expression Profiles ofInternational journal of molecular sciences · 2022Article
- Trihelix Transcriptional Factor GhGT26 of Cotton Enhances Salinity Tolerance inPlants (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrihelix transcription factor family is plant-specific and plays important roles in developmental processes. However, their function in abiotic stress response is largely unclear.
resultsWe studied one member GT-4 from Arabidopsis in relation to salt stress response. GT-4 expression is induced by salt stress and GT-4 protein is localized in nucleus and cytoplasm. GT-4 acts as a transcriptional activator and its C-terminal end is the activation domain. The protein can bind to the cis-elements GT-3 box, GT-3b box and MRE4. GT-4 confers enhanced salt tolerance in Arabidopsis likely through direct binding to the promoter and activation of Cor15A, in addition to possible regulation of other relevant genes. The gt-4 mutant shows salt sensitivity. TEM2, a member of AP2/ERF family was identified to interact with GT-4 in yeast two-hybrid, BiFC and Co-IP assays. Loss-of-function of TEM2 exerts no significant difference on salt tolerance or Cor15A expression in Arabidopsis. However, double mutant gt-4/tem2 shows greater sensitivity to salt stress and lower transcript level of Cor15A than gt-4 single mutant. GT-4 plus TEM2 can synergistically increase the promoter activity of Cor15A.
conclusionsGT-4 interacts with TEM2 and then co-regulates the salt responsive gene Cor15A to improve salt stress tolerance.
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