Evidence map›Paper›PMID 25465493›Full record

ArticleObesity research & clinical practice

The association between body composition and cystatin C in South Asians: results from the MASALA study.

Arti D Shah, Heidi Schmidt, Saunak Sen, Michael G Shlipak, Alka M Kanaya

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity research & clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Arti D ShahDivision of Endocrinology and Metabolism, University of California, San Francisco, United States. Electronic address: Arti.Shah@ucsf.edu.
Heidi SchmidtDivision of General Internal Medicine, Department of Medicine, University of California, San Francisco, United States.
Saunak SenDepartment of Epidemiology and Biostatistics, University of California, San Francisco, United States.
Michael G ShlipakDepartment of Epidemiology and Biostatistics, University of California, San Francisco, United States; Division of General Internal Medicine, San Francisco Veterans Affairs Medical Center, United States.
Alka M KanayaDivision of General Internal Medicine, Department of Medicine, University of California, San Francisco, United States; Department of Epidemiology and Biostatistics, University of California, San Francisco, United States.
University of California, San Francisco · USSan Francisco VA Medical Center · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GERMAN, MICHAEL S · 2003 to 2019
$21.8M
DIABETES, ENDOCRINOLOGY &METABOLISM TRAINING PROGRAMT32DK007418 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EDWARD C HSIAO · 1986 to 2026
$14.3M
Mediators of Atherosclerosis in South Asians Living in AmericaR01HL093009 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2010 to 2018
$5.4M
Ectopic fat and atherosclerosis in South AsiansK24HL112827 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2013 to 2022
$1.2M
Metabolic Syndrome and Atherosclerosis in South AsiansK23HL080026 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2006 to 2008
$442k
NCRR NIH HHS UL1 RR024131NHLBI NIH HHS K23 HL080026NHLBI NIH HHS K23 HL080026-01NHLBI NIH HHS K24 HL112827NHLBI NIH HHS K24HL112827NHLBI NIH HHS R01 HL093009NHLBI NIH HHS R01HL093009NIDDK NIH HHS 5T32DK007418NIDDK NIH HHS P30 DK063720NIDDK NIH HHS T32 DK007418
6 · The paper itself

Abstract

While South Asians have high rates of obesity and kidney disease, little is known about the effect of regional body composition on kidney function. We investigated the association between body composition measures and cystatin C-based estimated glomerular filtration rate (eGFRcysC) in 150 immigrant South Asians. The inverse association between overall adiposity and eGFRcysC was attenuated by C-reactive protein (CRP), while the association of ectopic fat was completely attenuated by metabolic covariates and CRP. In immigrant South Asians, the associations between overall adiposity and ectopic fat with decreased kidney function are largely explained by metabolic alterations and inflammation.

Indexed as

Asian PeopleBody CompositionGlomerular Filtration RateAdipose TissueAdiposityAgedAsiaCaliforniaC-Reactive ProteinCross-Sectional StudiesCystatin CEmigrants and ImmigrantsFemaleHumansInflammationKidneyC-Reactive ProteinCystatin CBody compositionCystatin CEctopic fatSouth Asian

Identifiers

PMID25465493
PMCPMC4404210
OpenAlexW2017047315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.