ReviewClinical EEG and neuroscience2015
Treatment of psychogenic nonepileptic seizures: updated review and findings from a mindfulness-based intervention case series.
Review in Clinical EEG and neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- A systematic review of brain stimulation in functional seizures.BMC neurology · 2026Pooled it
- The neurobiology of functional neurological disorders characterised by impaired awareness.Frontiers in psychiatry · 2023Pooled it
- Trial
- Electroclinical Dissociation in Generalized Epilepsy: A Video-EEG Case From Sub-Saharan Africa.Case reports in medicine · 2026Article
- Preliminary Findings from a Mindfulness-Based Intervention in Patients with Psychogenic Non-Epileptic Seizures.Neurology international · 2025Article
- Dissociative seizures mimicking epileptic seizures: diagnostic challenges in a case with atypical eye movements.Acta epileptologica · 2025Article
- Psychiatric Comorbidities in Functional Neurological Disorders and Psychogenic Non-Epileptic Seizures: A Systematic Review and Policy Recommendations for Improving Assessment and Treatment.Neuropsychiatric disease and treatment · 2024Review
- A Case Report of Psychogenic Non-epileptic Seizures in a 29-Year-Old Male With Schizophrenia.Cureus · 2023Article
- Functional Neurologic Disorders, disorders to be managed by neurologists, or are neurologists wandering in a dangerous field with inadequate resources?Frontiers in psychiatry · 2023Review
- Meditative and Mindfulness-Focused Interventions in Neurology: Principles, Science, and Patient Selection.Seminars in neurology · 2022Article
- Attachment style of patients diagnosed with psychogenic non-epileptic seizures at a tertiary Epilepsy Center in the Czech Republic.Frontiers in psychiatry · 2022Article
- Towards an Outpatient Model of Care for Motor Functional Neurological Disorders: A Neuropsychiatric Perspective.Neuropsychiatric disease and treatment · 2020Review
- Psychogenic Non-Epileptic Seizures; a Narrative Review.Archives of academic emergency medicine · 2020Review
- Article
- Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.Neurology · 2019Article
- Managing Functional Neurological Disorders: Protocol of a Cohort Study on Psychogenic Non-Epileptic Seizures Study.Neuropsychiatric disease and treatment · 2019Article
- Psychogenic nonepileptic seizures: a concise review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Review
- Clinical Approaches to Psychogenic Nonepileptic Seizures.Focus (American Psychiatric Publishing) · 2016Article
- Nonepileptic seizures: an updated review.CNS spectrums · 2016Review
- Medical management of epileptic seizures: challenges and solutions.Neuropsychiatric disease and treatment · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Psychogenic nonepileptic seizures (PNES) were first described in the medical literature in the 19th century, as seizure-like attacks not related to an identified central nervous system lesion, and are currently classified as a conversion disorder, according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). While a universally accepted and unifying etiological model does not yet exist, several risk factors have been identified. Management of PNES should be based on interdisciplinary collaboration, targeting modifiable risk factors. The first treatment phase in PNES is patient engagement, which is challenging given the demonstrated low rates of treatment retention. Acute interventions constitute the next phase in treatment, and most research studies focus on short-term evidence-based interventions. Randomized controlled pilot trials support cognitive-behavioral therapy. Other psychotherapeutic and psychopharmacological interventions have been less well-studied using controlled and uncontrolled trials. Within the discussion of acute interventions, we present a preliminary evaluation for feasibility of a mindfulness-based psychotherapy protocol in a very small sample of PNES patients. We demonstrated in 6 subjects that this intervention is feasible in real-life clinical scenarios and warrants further investigation in larger scale studies. The final treatment phase is long-term follow-up. Long-term outcome studies in PNES show that a significant proportion of patients remains symptomatic and experiences continued impairments in quality of life and functionality. We believe that PNES should be understood as a disease that requires different types of intervention during the various phases of treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.