Evidence map›Paper›PMID 25465066›Full record

ArticleBMC nephrology2014

From dialysis to transplantation: a 5-year longitudinal study on self-reported quality of life.

Nanna von der Lippe, Bård Waldum, Fredrik B Brekke, Amin A G Amro, Anna Varberg Reisæter, Ingrid Os

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
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  13. Itching in dialysis patients: impact on health-related quality of life and interactions with sleep problems and psychological symptoms-results from the RENINE/PROMs registry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
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  19. Modality transition on renal replacement therapy and quality of life of patients: a 10-year follow-up cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nanna von der LippeInstitute of Clinical Medicine, University of Oslo, Oslo, Norway. n.v.d.lippe@medisin.uio.no.
Bård Waldum
Fredrik B Brekke
Amin A G Amro
Anna Varberg Reisæter
Ingrid Os
University of Oslo · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known how health related quality of life (HRQOL) change in the transition from dialysis to renal transplantation (RTX). Longitudinal data addressing the patient-related outcomes are scarce, and particularly data regarding kidney-specific HRQOL are lacking. Thus, the aim of the current study was to assess HRQOL in patients followed from dialysis to RTX. Furthermore, to compare HRQOL in RTX patients and the general population.

methodsIn a prospective study, HRQOL was measured in a cohort of 110 patients (median age 53.5 (IQR 39-62) years, GFR 54 (45-72) ml/min/1.73 m2) in dialysis and after RTX using the self-administered Kidney Disease and Quality of Life Short Form version 1.3 (KDQOL-SF). Generic HRQOL in the RTX patients was compared to that of the general population (n=5903) using the SF-36. Clinical important change after RTX was defined as difference in HRQOL of SD/2.

resultsFollow-up time was 55 (IQR 50-59) months, and time after RTX was 41 (34-51) months. Four of nine domains in kidney-specific HRQOL improved after RTX, i.e. burden of kidney disease, effect of kidney disease, symptoms and work status. In SF-36, general health, vitality, social function and role physical improved after RTX, but none of the domains improved sufficiently to be regarded as clinically relevant change. There were highly significant differences in HRQOL between RTX patients and the general population after adjustment for age and gender for all items of SF-36 except for bodily pain and mental health.

conclusionsHRQOL improved in the transition from dialysis to transplantation, but clinical relevant change was only obtained in the kidney specific domains. HRQOL was perceived considerably poorer in RTX patients than in the general population. Our observations point to the need of improving HRQOL even after RTX, and should encourage further longitudinal research and clinical attention during treatment shift.

Indexed as

Quality of LifeAdultFemaleFollow-Up StudiesHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedNorwayProspective StudiesRenal DialysisSelf ReportSocial IsolationSurveys and Questionnaires

Identifiers

PMID25465066
PMCPMC4258806
OpenAlexW2006775168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.