Evidence map›Paper›PMID 25464979›Full record

ArticleAIDS research and human retroviruses2015

Short Communication: Current Prevalence and Risk Factors Associated with Human T Lymphotropic Virus Type 1 and Human T Lymphotropic Virus Type 2 Infections Among HIV/AIDS Patients in São Paulo, Brazil.

Adele Caterino-de-Araujo, Cláudio Tavares Sacchi, Maria Gisele Gonçalves, Karoline Rodrigues Campos, Mariana Cavalheiro Magri, Wong Kuen Alencar, Group of Surveillance and Diagnosis of HTLV of Sa˜o Paulo (GSuDiHTLV-SP)

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. HIV and Substance Use in Latin America: A Scoping Review.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Molecular detection of human T cell lymphotropic virus type 1 in pregnant women from Maranhão state, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adele Caterino-de-Araujo1 Centro de Imunologia, Instituto Adolfo Lutz , Secretaria de Estado da Saúde de São Paulo, São Paulo, SP, Brazil .
Cláudio Tavares Sacchi
Maria Gisele Gonçalves
Karoline Rodrigues Campos
Mariana Cavalheiro Magri
Wong Kuen Alencar
Group of Surveillance and Diagnosis of HTLV of Sa˜o Paulo (GSuDiHTLV-SP)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the 1990s, high prevalences of HIV/human T lymphotropic virus type 1 (HTLV-1) and HIV/human T lymphotropic virus type 2 (HTLV-2) coinfections were detected in São Paulo, Brazil in association with intravenous drug use (IDU). The current prevalences and risk factors for HIV/HTLV-1/-2 were evaluated in 1,608 patients attending the AIDS/STD Reference and Training Center in São Paulo. Blood samples were analyzed for HTLV-1/2-specific antibodies using enzyme immunoassays (EIA Murex HTLV-I+II, Diasorin, and Gold ELISA HTLV-I+II, REM) and immunoblotting (HTLV Blot 2.4, MP Biomedicals and INNO-LIA HTLV-I/II, Innogenetics) and for the pol proviral DNA segments of HTLV-1 and HTLV-2 by "in-house" real-time PCR. These analyses revealed that 50 (3.11%) of the samples were HTLV positive, including 25 (1.55%) that were HTLV-1 positive, 21 (1.31%) that were HTLV-2 positive, and 4 (0.25%) that were HTLV positive (untypeable). The median age of the HIV/HTLV-coinfected individuals was 50 years versus 44 years in the overall population (p=0.000). The risk factors associated with HIV/HTLV-1/-2 coinfections were female gender (OR 3.26, 1.78-5.95), black/pardo color (OR 2.21, 1.21-4.03), infection with hepatitis B virus (HBV) (OR 4.27, 2.32-7.87) or hepatitis C virus (HCV) (OR 24.40, 12.51-48.11), and intravenous drug use (IDU) (OR 30.01, 15.21-59.29). The current low prevalence of HTLV-1/2 in HIV-infected patients in São Paulo could be explained in part by programs providing IDUs with sterile needles and syringes and changes in the drug usage patterns of individuals from injecting cocaine to smoking crack cocaine.

Indexed as

AdultAgedAnimalsAntibodies, ViralBrazilCross-Sectional StudiesFemaleGene Products, polHIV InfectionsHTLV-II InfectionsHTLV-I InfectionsHumansImmunoblottingImmunoenzyme TechniquesMaleMiddle AgedAntibodies, ViralGene Products, pol

Identifiers

PMID25464979
PMCPMC4426329

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.