Evidence map›Paper›PMID 25464978›Full record

ArticleEpidemiology and infection2015

Clinical epidemiology and molecular profiling of human bocavirus in faecal samples from children with diarrhoea in Guangzhou, China.

D-M Zhang, M-M Ma, W-T Wen, X Zhu, L Xu, Z-J He, X He, J-H Wu, Y-W Hu, Y Zheng and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Sapovirus: an emerging cause of childhood diarrhea.Current opinion in infectious diseases · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

D-M ZhangDepartment of Medical Statistic and Epidemiology,School of Public Health, Sun Yat-sen University,Guangzhou,Guangdong,China.
M-M MaDepartment of Medical Statistic and Epidemiology,School of Public Health, Sun Yat-sen University,Guangzhou,Guangdong,China.
W-T WenKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
X ZhuKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
L XuKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
Z-J HeDepartment of Medical Statistic and Epidemiology,School of Public Health, Sun Yat-sen University,Guangzhou,Guangdong,China.
X HeDepartment of Clinical Laboratory,Sun Yat-sen University Cancer Centre,Guangzhou,Guangdong,China.
J-H WuKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
Y-W HuKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
Y ZhengKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
Y DengDepartment of Medical Statistic and Epidemiology,School of Public Health, Sun Yat-sen University,Guangzhou,Guangdong,China.
C-J LinKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
J-H LuDepartment of Medical Statistic and Epidemiology,School of Public Health, Sun Yat-sen University,Guangzhou,Guangdong,China.
M-F LiKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
K-Y CaoKey Laboratory for Tropical Disease Control,Ministry of Education,Guangzhou,Guangdong,China.
Ministry of Education of the People's Republic of China · CNSun Yat-sen University · CNSun Yat-sen University Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To understand the clinical epidemiology and molecular characteristics of human bocavirus (HBoV) infection in children with diarrhoea in Guangzhou, South China, we collected 1128 faecal specimens from children with diarrhoea from July 2010 to December 2012. HBoV and five other major enteric viruses were examined using real-time polymerase chain reaction. Human rotavirus (HRV) was the most prevalent pathogen, detected in 250 (22·2%) cases, followed by enteric adenovirus (EADV) in 76 (6·7%) cases, human astrovirus (HAstV) in 38 (3·4%) cases, HBoV in 17 (1·5%) cases, sapovirus (SaV) in 14 (1·2%) cases, and norovirus (NoV) in 9 (0·8%) cases. Co-infections were identified in 3·7% of the study population and 23·5% of HBoV-positive specimens. Phylogenetic analysis revealed 14 HBoV strains to be clustered into species HBoV1 with only minor variations among them. Overall, the detection of HBoV appears to partially contribute to the overall detection gap for enteric infections, single HBoV infection rarely results in severe clinical outcomes, and HBoV sequencing data appears to support conserved genomes across strains identified in this study.

Indexed as

AdenoviridaeAdenovirus Infections, HumanAdolescentAstroviridae InfectionsCaliciviridae InfectionsChildChild, PreschoolChinaCoinfectionCross-Sectional StudiesDiarrheaDNA, ViralFecesFemaleGastroenteritisHuman bocavirusDNA, ViralRNA, ViralChildrendiarrhoeahuman bocavirusphylogenetic analysis

Identifiers

PMID25464978
PMCPMC9150985
OpenAlexW2094685335

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.