Evidence map›Paper›PMID 25464130›Full record

ArticleInternational journal of environmental research and public health2014

Exploration of preterm birth rates using the public health exposome database and computational analysis methods.

Anne D Kershenbaum, Michael A Langston, Robert S Levine, Arnold M Saxton, Tonny J Oyana, Barbara J Kilbourne, Gary L Rogers, Lisaann S Gittner, Suzanne H Baktash, Patricia Matthews-Juarez and 1 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Using exposomics to assess cumulative risks and promote health.Environmental and molecular mutagenesis · 2015
    Article
  13. The public health exposome: a population-based, exposure science approach to health disparities research.International journal of environmental research and public health · 2014
    Article
  14. Scalable combinatorial tools for health disparities research.International journal of environmental research and public health · 2014
    Article
  15. Article
  16. Geographic Hotspots for Low Birthweight: An Analysis of Counties With Persistently High Rates.Inquiry : a journal of medical care organization, provision and financing
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne D KershenbaumDepartment of Public Health, University of Tennessee, Knoxville, TN 37996, USA. annekersh@gmail.com.
Michael A LangstonDepartment of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN 37996, USA. langston@eecs.utk.edu.
Robert S LevineDepartment of Family and Community Medicine, Meharry Medical College, Nashville, TN 37208, USA. rlevine@mmc.edu.
Arnold M SaxtonDepartment of Animal Science, Institute of Agriculture, University of Tennessee, Knoxville, TN 37996, USA. asaxton@utk.edu.
Tonny J OyanaResearch Center on Health Disparities, Equity, and the Exposome, University of Tennessee Health Science Center, Memphis, TN 38163, USA. toyana@uthsc.edu.
Barbara J KilbourneDepartment of Family and Community Medicine, Meharry Medical College, Nashville, TN 37208, USA. bkilbourne@mmc.edu.
Gary L RogersNational Institute for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA. grogers3@utk.edu.
Lisaann S GittnerDepartment of Political Sciences, Texas Tech University, Lubbock, TX 79409, USA. lisa.gittner@ttu.edu.
Suzanne H BaktashDepartment of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN 37996, USA. sbaktash@utk.edu.
Patricia Matthews-JuarezResearch Center on Health Disparities, Equity, and the Exposome, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Paul D JuarezResearch Center on Health Disparities, Equity, and the Exposome, University of Tennessee Health Science Center, Memphis, TN 38163, USA. pjuarez@uthsc.edu.

Funding

Training/Education CoreP20MD000516 · NIMHD · MEHARRY MEDICAL COLLEGE · PI ZOOROB, ROGER J · 2003 to 2013
$14.2M
Data Structures, Algorithms and Tools for Ontological DiscoveryR01AA018776 · NIAAA · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2010 to 2019
$3.9M
NIAAA NIH HHS R01 AA018776NIAAA NIH HHS R01AA018776NIMHD NIH HHS P20 MD000516
6 · The paper itself

Abstract

Recent advances in informatics technology has made it possible to integrate, manipulate, and analyze variables from a wide range of scientific disciplines allowing for the examination of complex social problems such as health disparities. This study used 589 county-level variables to identify and compare geographical variation of high and low preterm birth rates. Data were collected from a number of publically available sources, bringing together natality outcomes with attributes of the natural, built, social, and policy environments. Singleton early premature county birth rate, in counties with population size over 100,000 persons provided the dependent variable. Graph theoretical techniques were used to identify a wide range of predictor variables from various domains, including black proportion, obesity and diabetes, sexually transmitted infection rates, mother's age, income, marriage rates, pollution and temperature among others. Dense subgraphs (paracliques) representing groups of highly correlated variables were resolved into latent factors, which were then used to build a regression model explaining prematurity (R-squared = 76.7%). Two lists of counties with large positive and large negative residuals, indicating unusual prematurity rates given their circumstances, may serve as a starting point for ways to intervene and reduce health disparities for preterm births.

Indexed as

Databases, FactualModels, TheoreticalFemaleHumansInfant, NewbornInfant, PrematureLogistic ModelsPopulation SurveillancePregnancyPregnancy OutcomePremature BirthPublic Health AdministrationRisk FactorsUnited States

Identifiers

PMID25464130
PMCPMC4276617

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.