ReviewJournal of molecular and cellular cardiology2015
The mitochondrial Ca(2+) uniporter complex.
Review in Journal of molecular and cellular cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 99 citations in OpenAlex.
- Enhancement of mitochondrial calcium uptake is cardioprotective against maladaptive hypertrophy by retrograde signaling uptuning Akt.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Channels of Evolution: Unveiling Evolutionary Patterns in Diatom CaPlants (Basel, Switzerland) · 2024Article
- Association betweenGenes · 2024Article
- Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)PThe Journal of biological chemistry · 2023Article
- MICU1 occludes the mitochondrial calcium uniporter in divalent-free conditions.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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- Article
- Mitochondrial Calcium: Effects of Its Imbalance in Disease.Antioxidants (Basel, Switzerland) · 2022Review
- Mitochondria modulate ameloblast CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Article
- Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer.Free radical biology & medicine · 2021Article
- In vivo brain imaging of mitochondrial CaBiochimica et biophysica acta. Molecular cell research · 2021Review
- RIPK3 Activates MLKL-mediated Necroptosis and Inflammasome Signaling duringAmerican journal of respiratory cell and molecular biology · 2021Article
- Mitochondria: Insights into Crucial Features to Overcome Cancer Chemoresistance.International journal of molecular sciences · 2021Review
- Molecular machinery regulating mitochondrial calcium levels: The nuts and bolts of mitochondrial calcium dynamics.Mitochondrion · 2021Review
- Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria CaScience signaling · 2020Article
- Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity.Journal of molecular and cellular cardiology · 2020Article
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- Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease.Nature communications · 2020Article
- Mitochondrial Dysfunction in Age-Related Metabolic Disorders.Proteomics · 2020Review
- Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Calcium influx into the mitochondrial matrix plays important roles in the regulation of cell death pathways, bioenergetics and cytoplasmic Ca(2+) signals. During the last few years, several molecular components of the inner membrane mitochondrial Ca(2+) uniporter, the dominant pathway for Ca(2+) influx into the mitochondrial matrix, have been identified. The uniporter is now recognized as a complex of proteins that include a Ca(2+) pore forming component and accessory proteins that are either required for its channel activity or regulate it under various conditions. This review summarizes recent discoveries about the molecular basis of the uniporter complex. This article is part of a Special Issue entitled "Mitochondria: From Basic Mitochondrial Biology to Cardiovascular Disease."
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.