Evidence map›Paper›PMID 25462798›Full record

ArticleNeuroImage2015

The strategy and motivational influences on the beneficial effect of neurostimulation: a tDCS and fNIRS study.

Kevin T Jones, Filiz Gözenman, Marian E Berryhill

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin T JonesDepartment of Psychology, Program in Cognitive and Brain Sciences, University of Nevada, Reno, 1664 North Virginia Street, NV 89557, USA; Department of Neurology, Center for Aphasia Research and Rehabilitation, Georgetown University Medical Center, 4000 Reservoir Road NW, Washington, D.C. 20057, USA. Electronic address: kevjones22@gmail.com.
Filiz GözenmanDepartment of Psychology, Program in Cognitive and Brain Sciences, University of Nevada, Reno, 1664 North Virginia Street, NV 89557, USA.
Marian E BerryhillDepartment of Psychology, Program in Cognitive and Brain Sciences, University of Nevada, Reno, 1664 North Virginia Street, NV 89557, USA.

Funding

Virtual Reality and Augmented Reality CoreP20GM103650 · NIGMS · UNIVERSITY OF NEVADA RENO · PI WEBSTER, MICHAEL A · 2012 to 2022
$20.9M
Investigating Working Memory Encoding using Frequency-Tagging of Evoked ResponseR15EY022775 · NEI · UNIVERSITY OF NEVADA RENO · PI BERRYHILL, MARIAN E, CAPLOVITZ, GIDEON PAUL · 2012 to 2012
$407k
NEI NIH HHS NEI R15EY022775NEI NIH HHS R15 EY022775NIGMS NIH HHS NIH P20GM103650NIGMS NIH HHS P20 GM103650
6 · The paper itself

Abstract

Working memory (WM) capacity falls along a spectrum with some people demonstrating higher and others lower WM capacity. Efforts to improve WM include applying transcranial direct current stimulation (tDCS), in which small amounts of current modulate the activity of underlying neurons and enhance cognitive function. However, not everyone benefits equally from a given tDCS protocol. Recent findings revealed tDCS-related WM benefits for individuals with higher working memory (WM) capacity. Here, we test two hypotheses regarding those with low WM capacity to see if they too would benefit under more optimal conditions. We tested whether supplying a WM strategy (Experiment 1) or providing greater extrinsic motivation through incentives (Experiment 2) would restore tDCS benefit to the low WM capacity group. We also employed functional near infrared spectroscopy to monitor tDCS-induced changes in neural activity. Experiment 1 demonstrated that supplying a WM strategy improved the high WM capacity participants' accuracy and the amount of oxygenated blood levels following anodal tDCS, but it did not restore tDCS-linked WM benefits to the low WM capacity group. Experiment 2 demonstrated that financial motivation enhanced performance in both low and high WM capacity groups, especially after anodal tDCS. Here, only the low WM capacity participants showed a generalized increase in oxygenated blood flow across both low and high motivation conditions. These results indicate that ensuring that participants' incentives are high may expand cognitive benefits associated with tDCS. This finding is relevant for translational work using tDCS in clinical populations, in which motivation can be a concern.

Indexed as

AdultBrainElectric StimulationFemaleHumansMaleMemory, Short-TermMotivationPsychomotor PerformanceSpectroscopy, Near-InfraredYoung AdultFunctional near infrared spectroscopyTranscranial direct current stimulationWorking memoryWorking memory capacity

Identifiers

PMID25462798
PMCPMC4262534

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.