ArticleNeuroImage2015
Theoretical and experimental evaluation of multi-band EPI for high-resolution whole brain pCASL Imaging.
Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 46 citations in OpenAlex.
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- Choroid plexus aging: structural and vascular insights from the HCP-aging dataset.Fluids and barriers of the CNS · 2024Article
- Diurnal Variation of Brain Activity in the Human Suprachiasmatic Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Comparing single- and multi-post labeling delays for the measurements of resting cerebral and hippocampal blood flow for cerebrovascular testing in midlife adults.Frontiers in physiology · 2024Article
- Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee.Seminars in musculoskeletal radiology · 2023Review
- Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation.Frontiers in physiology · 2023Article
- Impaired Neurovascular Function Underlies Poor Neurocognitive Outcomes and Is Associated with Nitric Oxide Bioavailability in Congenital Heart Disease.Metabolites · 2022Article
- The comorbidity and cognition in multiple sclerosis (CCOMS) neuroimaging protocol: Study rationale, MRI acquisition, and minimal image processing pipelines.Frontiers in neuroimaging · 2022Article
- Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy.Brain topography · 2021Article
- Comparison of 2D simultaneous multi-slice and 3D GRASE readout schemes for pseudo-continuous arterial spin labeling of cerebral perfusion at 3 T.Magma (New York, N.Y.) · 2021Article
- Epileptogenic zone detection in MRI negative epilepsy using adaptive thresholding of arterial spin labeling data.Scientific reports · 2021Article
- Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD.Current Alzheimer research · 2021Article
- Super-Resolution Arterial Spin Labeling Using Slice-Dithered Enhanced Resolution and Simultaneous Multi-Slice Acquisition.Frontiers in neuroscience · 2021Article
- 7T bone perfusion imaging of the knee using arterial spin labeling MRI.Magnetic resonance in medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Multi-band echo planar imaging (MB-EPI), a new approach to increase data acquisition efficiency and/or temporal resolution, has the potential to overcome critical limitations of standard acquisition strategies for obtaining high-resolution whole brain perfusion imaging using arterial spin labeling (ASL). However, the use of MB also introduces confounding effects, such as spatially varying amplified thermal noise and leakage contamination, which have not been evaluated to date as to their effect on cerebral blood flow (CBF) estimation. In this study, both the potential benefits and confounding effects of MB-EPI were systematically evaluated through both simulation and experimentally using a pseudo-continuous arterial spin labeling (pCASL) strategy. These studies revealed that the amplified noise, given by the geometry factor (g-factor), and the leakage contamination, assessed by the total leakage factor (TLF), have a minimal impact on CBF estimation. Furthermore, it is demonstrated that MB-EPI greatly benefits high-resolution whole brain pCASL studies in terms of improved spatial and temporal signal-to-noise ratio efficiencies, and increases compliance with the assumptions of the commonly used single blood compartment model, resulting in improved CBF estimates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.