Evidence map›Paper›PMID 25460818›Full record

ReviewInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2015

Molecular epidemiology and genomics of group A Streptococcus.

Debra E Bessen, W Michael McShan, Scott V Nguyen, Amol Shetty, Sonia Agrawal, Hervé Tettelin

Abstract readReview
In one paragraph

Review in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Frontiers in public health · 2023
    Pooled it
  2. Trial
  3. Article
  4. M1 protein from group ABlood vessels, thrombosis & hemostasis · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. [A rare cause of acute abdomen in a young immunocompetent woman].Innere Medizin (Heidelberg, Germany) · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Genomic analysis of group AJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  16. Article
  17. Invasive Streptococcus pyogenes disease in Spain: a microbiological and epidemiological study covering the period 2007-2019.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  18. Article
  19. Article
  20. [The bacteriological characteristics and drug resistance of the nasopharyngeal region in 311 cases of adenoid hypertrophy with secretory otitis media].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Debra E BessenDepartment of Microbiology & Immunology, New York Medical College, Valhalla, NY 10595, USA. Electronic address: debra_bessen@nymc.edu.
W Michael McShanUniversity of Oklahoma Health Sciences Center, Department of Pharmaceutical Sciences, College of Pharmacy, Oklahoma City, OK 73117, USA. Electronic address: William-McShan@ouhsc.edu.
Scott V NguyenUniversity of Oklahoma Health Sciences Center, Department of Pharmaceutical Sciences, College of Pharmacy, Oklahoma City, OK 73117, USA. Electronic address: Scott-Van-Nguyen@ouhsc.edu.
Amol ShettyInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: AShetty@som.umaryland.edu.
Sonia AgrawalInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: SAgrawal@som.umaryland.edu.
Hervé TettelinInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: tettelin@som.umaryland.edu.

Funding

Population genomics of Streptococcus pyogenesR01AI065572 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2005 to 2009
$1.8M
Tissue-Specific Infection by Group A StreptococciR01AI053826 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2003 to 2007
$1.3M
EVOLUTION OF GROUP A STREPTOCOCCIR01GM060793 · NIGMS · YALE UNIVERSITY · PI BESSEN, DEBRA E · 2000 to 2004
$1.1M
Bacteriophage Control of DNA Repair in Streptococcus PyogenesR15AI072718 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MCSHAN, WILLIAM MICHAEL · 2007 to 2013
$1.0M
Tissue-Specific Infection by Group A StreptococciR56AI053826 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2008 to 2009
$808k
Molecular Evolution of Resistance in Strep. pyogenesR21AI061454 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2004 to 2005
$429k
NIAID NIH HHS AI053826NIAID NIH HHS AI061454NIAID NIH HHS AI065572NIAID NIH HHS AI072718NIAID NIH HHS R01 AI053826NIAID NIH HHS R01 AI065572NIAID NIH HHS R15 AI072718NIAID NIH HHS R21 AI061454NIAID NIH HHS R56 AI053826NIGMS NIH HHS GM060793NIGMS NIH HHS R01 GM060793
6 · The paper itself

Abstract

Streptococcus pyogenes (group A Streptococcus; GAS) is a strict human pathogen with a very high prevalence worldwide. This review highlights the genetic organization of the species and the important ecological considerations that impact its evolution. Recent advances are presented on the topics of molecular epidemiology, population biology, molecular basis for genetic change, genome structure and genetic flux, phylogenomics and closely related streptococcal species, and the long- and short-term evolution of GAS. The application of whole genome sequence data to addressing key biological questions is discussed.

Indexed as

Genome, BacterialGenomicsBacteriophagesBiological EvolutionDisease OutbreaksDNA Transposable ElementsGenetic VariationHigh-Throughput Nucleotide SequencingHumansMolecular EpidemiologyPhylogenySelection, GeneticStreptococcal InfectionsStreptococcus pyogenesVirulenceDNA Transposable ElementsEpidemiologyEvolutionGenomicsGroup A StreptococcusPopulation biologyStreptococcus pyogenes

Identifiers

PMID25460818
PMCPMC4416080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.