ArticleEnvironmental research2015
Regional PM2.5 and asthma morbidity in an agricultural community: a panel study.
Article in Environmental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Randomized trial of a portable HEPA air cleaner intervention to reduce asthma morbidity among Latino children in an agricultural community.Environmental health : a global access science source · 2022Trial
- Trial
- Effectiveness of portable HEPA air cleaners on reducing indoor PMIndoor air · 2021Trial
- Air pollution from livestock farms and lung function decline in neighboring residents over 7 years.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Article
- Article
- Inter-continental variability in the relationship of oxidative potential and cytotoxicity with PMNature communications · 2024Article
- Antiracist Research and Practice for Environmental Health: Implications for Community Engagement.Environmental health perspectives · 2023Article
- Identifying the causal effects of long-term exposure to PMBMC medicine · 2023Article
- Adult asthma associated with roadway density and housing in rural Appalachia: the Mountain Air Project (MAP).Environmental health : a global access science source · 2023Article
- Article
- Modeling and forecasting of monthly PMEnvironmental monitoring and assessment · 2021Article
- Airway hyperresponsiveness development and the toxicity of PM2.5.Environmental science and pollution research international · 2021Review
- Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults.Particle and fibre toxicology · 2020Article
- The joint effect of ambient air pollution and agricultural pesticide exposures on lung function among children with asthma.Environmental research · 2020Article
- Double decomposition and optimal combination ensemble learning approach for interval-valued AQI forecasting using streaming data.Environmental science and pollution research international · 2020Article
- The home air in agriculture pediatric intervention (HAPI) trial: Rationale and methods.Contemporary clinical trials · 2020Article
- Measuring the Urban Particulate Matter Island Effect with Rapid Urban Expansion.International journal of environmental research and public health · 2020Article
- Estimated time-varying exposures to air emissions from animal feeding operations and childhood asthma.International journal of hygiene and environmental health · 2020Article
- Short-term effect of PMEnvironmental science and pollution research international · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundElevated pediatric asthma morbidity has been observed in rural US communities, but the role of the ambient environment in exacerbating rural asthma is poorly understood.
objectivesTo investigate associations between particulate matter less than 2.5 μm in diameter (PM2.5) and pediatric asthma exacerbations in an agricultural community of Washington State.
methodsSchool-aged children with asthma (n=58) were followed for up to 25 months with repeated measures of respiratory health. Asthma symptoms and quick-relief medication use were assessed biweekly through phone administered surveys (n=2023 interviews). In addition, subjects used home peak flow meters on a daily basis to measure forced expiratory volume in one second (FEV1) (n=7830 measurements). Regional PM2.5 was measured at a single air monitor located centrally in the study region. To assess relationships between PM2.5 and these outcomes we used linear regression with generalized estimating equations, adjusting for meteorological and temporal confounders. Effect modification by atopy was explored as well.
resultsAn interquartile increase (IQR) in weekly PM2.5 of 6.7 μg/m(3) was associated with an increase in reported asthma symptoms Specific symptoms including wheezing, limitation of activities, and nighttime waking displayed the strongest associations. FEV1 as a percent of predicted decreased by 0.9% (95%CI: -1.8, 0.0) for an IQR increase in PM2.5 one day prior, and by 1.4% (95%CI: -2.7, -0.2) when restricted to children with atopic asthma.
conclusionsThis study provides evidence that PM2.5 in an agricultural setting contributes to elevated asthma morbidity. Further work on identifying and mitigating sources of PM2.5 in the area is warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.