Evidence map›Paper›PMID 25460415›Full record

ArticleJournal of the mechanical behavior of biomedical materials2015

Imaging, spectroscopy, mechanical, alignment and biocompatibility studies of electrospun medical grade polyurethane (Carbothane™ 3575A) nanofibers and composite nanofibers containing multiwalled carbon nanotubes.

Faheem A Sheikh, Javier Macossay, Travis Cantu, Xujun Zhang, M Shamshi Hassan, M Esther Salinas, Chakavak S Farhangi, Hassan Ahmad, Hern Kim, Gary L Bowlin

Abstract read
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In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Tissue engineering. Part A · 2017
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Faheem A SheikhDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA; Nano-Bio Regenerative Medical Institute, College of Medicine, Hallym University, Chuncheon 200-702, South Korea. Electronic address: faheem99in@yahoo.com.
Javier MacossayDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA. Electronic address: jmacossay@utpa.edu.
Travis CantuDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA.
Xujun ZhangDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA.
M Shamshi HassanDepartment of Organic Materials and Fiber Engineering, Chonbuk National University, Jeonju 561-756, South Korea.
M Esther SalinasDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA.
Chakavak S FarhangiDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA.
Hassan AhmadDepartment of Chemistry, University of Texas-Pan American, Edinburg, TX 78539, USA.
Hern KimEnergy and Environment Fusion Technology Center, Department of Energy and Biotechnology, Myongji University, Yongin, Kyonggi-do 449-728, South Korea.
Gary L BowlinDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.

Funding

ELECTROSPINNING ARTIFICIAL LIGAMENTS AND TENDONS FOR POTENTIAL PROSTHESESSC2AG036825 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI MACOSSAY-TORRES, JAVIER · 2009 to 2011
$425k
NIA NIH HHS 1SC2AG036825-01NIA NIH HHS SC2 AG036825
6 · The paper itself

Abstract

In the present study, we discuss the electrospinning of medical grade polyurethane (Carbothane™ 3575A) nanofibers containing multi-walled-carbon-nanotubes (MWCNTs). A simple method that does not depend on additional foreign chemicals has been employed to disperse MWCNTs through high intensity sonication. Typically, a polymer solution consisting of polymer/MWCNTs has been electrospun to form nanofibers. Physiochemical aspects of prepared nanofibers were evaluated by SEM, TEM, FT-IR and Raman spectroscopy, confirming nanofibers containing MWCNTs. The biocompatibility and cell attachment of the produced nanofiber mats were investigated while culturing them in the presence of NIH 3T3 fibroblasts. The results from these tests indicated non-toxic behavior of the prepared nanofiber mats and had a significant attachment of cells towards nanofibers. The incorporation of MWCNTs into polymeric nanofibers led to an improvement in tensile stress from 11.40 ± 0.9 to 51.25 ± 5.5 MPa. Furthermore, complete alignment of the nanofibers resulted in an enhancement on tensile stress to 72.78 ± 5.5 MPa. Displaying these attributes of high mechanical properties and non-toxic nature of nanofibers are recommended for an ideal candidate for future tendon and ligament grafts.

Indexed as

ElectricityMaterials TestingMicroscopySpectrum AnalysisAnimalsCell AdhesionCell SurvivalMechanical PhenomenaMiceNanofibersNanotechnologyNanotubes, CarbonNIH 3T3 CellsPolyurethanesNanotubes, CarbonPolyurethanesCytotoxicityDispersionElectrospinningMechanical propertiesNanofibers

Identifiers

PMID25460415
PMCPMC4312223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.