Evidence map›Paper›PMID 25460291›Full record

ReviewHormone molecular biology and clinical investigation2014

Sex and sex steroids: impact on the kinetics of fatty acids underlying body shape.

Sylvia Santosa, Michael D Jensen

Abstract readReview
In one paragraph

Review in Hormone molecular biology and clinical investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2018
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sylvia Santosa
Michael D Jensen

Funding

REGIONAL FATTY ACID METABOLISM IN HUMANSR01DK045343 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1992 to 2026
$12.9M
FFA METABOLISM IN DIFFERENT TYPES OF HUMAN OBESITYR01DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1993 to 2026
$8.2M
Free Fatty Acid Metabolism in Different Types of Human ObesityR37DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI JENSEN, MICHAEL D. · 2003 to 2012
$4.1M
FFA METABOLISM IN DIFFERENT TYPES OF HUMAN OBESITYR29DK040484 · NIDDK · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI JENSEN, MICHAEL D. · 1988 to 1992
–
NIDDK NIH HHS DK40484NIDDK NIH HHS DK45343NIDDK NIH HHS R01 DK040484NIDDK NIH HHS R01 DK045343NIDDK NIH HHS R37 DK040484
6 · The paper itself

Abstract

Adult humans have a remarkable sexual dimorphism in body shape. Men tend to store relatively more fat in the upper body whereas women store more fat in the lower body. We do not have a complete understanding of the mechanisms underlying these differences, but we know that people who preferentially store abdominal fat are at greater risk of metabolic disease. It is also known that the changes in sex steroid concentrations during puberty and again with advancing age are accompanied by changes in body fat distribution. The objective of this review is to describe what has been learned regarding the mechanisms underlying changes in regional body fat distribution that occur as a result of changes in sex hormones and to delineate effects of sex steroids in modulating body composition.

Indexed as

Sex CharacteristicsAdipose TissueBody CompositionBody Fat DistributionDisease SusceptibilityFatty AcidsFemaleGonadal Steroid HormonesHumansLipid MetabolismMaleSex FactorsFatty AcidsGonadal Steroid Hormones

Identifiers

PMID25460291
PMCPMC4348027

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.