ReviewCurrent opinion in pharmacology2014
Transgenerational effects of obesogens and the obesity epidemic.
Review in Current opinion in pharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
- Combined Exposure to Endocrine Disruptors, BPA and BP-3, during Pregnancy and Lactation Alters Postnatal Body Mass, Growth, White Adipose Tissue Morphology, and Adipogenic Gene Expression in a Sex-Specific Manner.Environment & health (Washington, D.C.) · 2026Article
- Systemic impacts of diabetes on spermatogenesis and intervention strategies: multilayered mechanism analysis and cutting-edge therapeutic approaches.Reproductive biology and endocrinology : RB&E · 2025Review
- Tetramethyl Bisphenol F: Organ- and System-Specific Toxicity, Current Status, and Perspectives.International journal of molecular sciences · 2025Review
- DNA Methylation: A Key Regulator in Male and Female Reproductive Outcomes.Life (Basel, Switzerland) · 2025Review
- Increased susceptibility to prostate cancer biomarkers in the offspring of male mouse progenitors with lifelong or early life exposure to high-fat diet.European journal of nutrition · 2025Article
- Transgenerational Effects of the Obesogen Tributyltin on Metabolic Health in Mice: Interactions With a Western Diet.Endocrinology · 2025Article
- Tributyltin Enhances Macrophage Inflammation and Lipolysis, Contributing to Adipose Tissue Dysfunction.Journal of the Endocrine Society · 2024Article
- Decoding the Influence of Obesity on Prostate Cancer and Its Transgenerational Impact.Nutrients · 2023Review
- Obesogens in Foods.Biomolecules · 2022Review
- Male Infertility in the XXI Century: Are Obesogens to Blame?International journal of molecular sciences · 2022Review
- Review
- Higher maternal BMI early in pregnancy is associated with overweight and obesity in young adult offspring in Thailand.BMC public health · 2021Article
- Adipose Tissue and Endocrine-Disrupting Chemicals: Does Sex Matter?International journal of environmental research and public health · 2020Review
- Agrochemicals and obesity.Molecular and cellular endocrinology · 2020Review
- Article
- Interaction of volatile organic compounds and underlying liver disease: a new paradigm for risk.Biological chemistry · 2018Review
- Sarcopoterium spinosum extract improved insulin sensitivity in mice models of glucose intolerance and diabetes.PloS one · 2018Article
- Persistent Organic Pollutants and Type 2 Diabetes: A Critical Review of Review Articles.Frontiers in endocrinology · 2018Review
- Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice.Nature communications · 2017Article
- Endocrine Disrupting Chemicals, Transgenerational Epigenetics and Metabolic Diseases.EC endocrinology and metabolic research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the last three decades there has been a dramatic, worldwide increase in the incidence of obesity, particularly in Western societies. This trend has required a significant economic investment to treat obesity-related disorders such as type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver disease. There is an urgent need to understand the factors that contribute to this increase in obesity in order to find new tools that will improve quality of life in affected individuals and to avoid the propagation of obesity to future generations. Endocrine disrupting chemicals have become an important piece of the obesity epidemic puzzle but little is known about the mechanism underlying their effects. In this commentary, we highlight recent work showing that the consequences of ancestral exposure to obesogenic chemicals results in the transmission of obesity-related phenotypes through at least three generations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.