Evidence map›Paper›PMID 25460072›Full record

ReviewCurrent opinion in neurobiology2015

Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms.

Eve Marder, Marie L Goeritz, Adriane G Otopalik

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Reductionism in Engram Neuroscience.The European journal of neuroscience · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Modulation by Neuropeptides with Overlapping Targets Results in Functional Overlap in Oscillatory Circuit Activation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Energy-efficient network activity from disparate circuit parameters.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Review

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eve MarderVolen Center and Biology Department, Brandeis University, Waltham, MA 02454, United States. Electronic address: marder@brandeis.edu.
Marie L GoeritzVolen Center and Biology Department, Brandeis University, Waltham, MA 02454, United States.
Adriane G OtopalikVolen Center and Biology Department, Brandeis University, Waltham, MA 02454, United States.

Funding

NEUROSCIENCE: FROM CHANNELS TO BEHAVIORT32MH019929 · NIMH · BRANDEIS UNIVERSITY · PI GRIFFITH, LESLIE C · 1994 to 2023
$8.5M
Variability and Compensation in Reliable Neuronal NetworksR01MH046742 · NIMH · BRANDEIS UNIVERSITY · PI MARDER, EVE E · 1990 to 2025
$7.8M
NEUROTRANSMITTER MODULATION OF NEURONAL CIRCUITSR01NS017813 · NINDS · BRANDEIS UNIVERSITY · PI MARDER, EVE E · 1985 to 2009
$3.3M
Neurotransmitter Modulation of Neuronal CircuitsR37NS017813 · NINDS · BRANDEIS UNIVERSITY · PI MARDER, EVE E · 2010 to 2016
$2.6M
Undergraduate and Graduate Training in Computational NeuroscienceT90DA032435 · NIDA · BRANDEIS UNIVERSITY · PI MILLER, PAUL · 2011 to 2020
$1.6M
INTRINSIC PLASTICITY IN OSCILLATORY NEURAL NETWORKSR37MH046742 · NIMH · BRANDEIS UNIVERSITY · PI MARDER, EVE E · 1995 to 2004
$1.5M
NIDA NIH HHS T90 DA032435NIMH NIH HHS MH46742NIMH NIH HHS R01 MH046742NIMH NIH HHS R37 MH046742NIMH NIH HHS T32 MH019929NINDS NIH HHS NS17813NINDS NIH HHS R01 NS017813NINDS NIH HHS R37 NS017813
6 · The paper itself

Abstract

Small central pattern generating circuits found in invertebrates have significant advantages for the study of the circuit mechanisms that generate brain rhythms. Experimental and computational studies of small oscillatory circuits reveal that similar rhythms can arise from disparate mechanisms. Animal-to-animal variation in the properties of single neurons and synapses may underly robust circuit performance, and can be revealed by perturbations. Neuromodulation can produce altered circuit performance but also ensure reliable circuit function.

Indexed as

Models, NeurologicalAction PotentialsAnimalsBrainCentral Pattern GeneratorsComputer Simulation

Identifiers

PMID25460072
PMCPMC4375070

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.