ReviewClinics in perinatology2014
Probiotics and necrotizing enterocolitis.
Review in Clinics in perinatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of probiotics on experimental necrotizing enterocolitis: a systematic review and meta-analysis.Pediatric research · 2018Pooled it
- Effect of Saccharomyces boulardii and Mode of Delivery on the Early Development of the Gut Microbial Community in Preterm Infants.PloS one · 2016Trial
- Emerging Prospects for Combating Fungal Infections by Targeting Phosphatidylinositol Transfer Proteins.International journal of molecular sciences · 2021Review
- Cost-effectiveness of probiotics for necrotizing enterocolitis prevention in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Necrotizing enterocolitis: It's not all in the gut.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Toll-Like Receptor-Mediated Intestinal Inflammatory Imbalance in the Pathogenesis of Necrotizing Enterocolitis.Cellular and molecular gastroenterology and hepatology · 2018Review
- Gastrointestinal Organoids: Understanding the Molecular Basis of the Host-Microbe Interface.Cellular and molecular gastroenterology and hepatology · 2017Review
- Innate Immunity and Breast Milk.Frontiers in immunology · 2017Review
- Colonization with Escherichia coli EC 25 protects neonatal rats from necrotizing enterocolitis.PloS one · 2017Article
- Necrotizing enterocolitis: new insights into pathogenesis and mechanisms.Nature reviews. Gastroenterology & hepatology · 2016Review
- Nasogastric feeding tubes from a neonatal department yield high concentrations of potentially pathogenic bacteria- even 1 d after insertion.Pediatric research · 2016Observational
- Necrotising enterocolitis and mortality in preterm infants after introduction of probiotics: a quasi-experimental study.Scientific reports · 2016Observational
- Challenges of infant nutrition research: a commentary.Nutrition journal · 2016Review
- Benefits of Bifidobacterium breve M-16V Supplementation in Preterm Neonates - A Retrospective Cohort Study.PloS one · 2016Article
- Pathogenesis of neonatal necrotizing enterocolitis.Pediatric surgery international · 2015Review
- Notes from the field: Fatal gastrointestinal mucormycosis in a premature infant associated with a contaminated dietary supplement--Connecticut, 2014.MMWR. Morbidity and mortality weekly report · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
One of the most controversial areas in neonatology is whether probiotics should be provided routinely to preterm infants to prevent necrotizing enterocolitis (NEC). This review provides the reader with a brief overview of NEC and current concepts of its pathophysiology, discusses the microbial ecology of the intestine in preterm infants and factors that may lead to a "dysbiosis", summarizes studies of probiotics in preterm infants, elaborates on the need for regulation in this area, and discusses alternatives to probiotics and what is the future for the prevention of NEC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.