ReviewImmunology and allergy clinics of North America2015
The role of the early-life environment in the development of allergic disease.
Review in Immunology and allergy clinics of North America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Indoor Allergen Interventions in Homes and Schools for Managing Asthma.The journal of allergy and clinical immunology. In practice · 2025Review
- Review
- Effects of Pollution on Pregnancy and Infants.Cureus · 2023Review
- Influence of the environment on the characteristics of asthma.Scientific reports · 2022Article
- Knowledge mapping of the links between the microbiota and allergic diseases: A bibliometric analysis (2002-2021).Frontiers in immunology · 2022Article
- Vitamin D and Microbiota: Is There a Link with Allergies?International journal of molecular sciences · 2021Review
- Association of diabetes-related autoantibodies with the incidence of asthma, eczema and allergic rhinitis in the TRIGR randomised clinical trial.Diabetologia · 2020Article
- Effects of gut microbiome and environment on the development of eczema in Chinese infants.Medicine · 2020Article
- Expectations versus Reality: Long-Term Research on the Dog-Owner Relationship.Animals : an open access journal from MDPI · 2020Article
- Asthma epidemiology and risk factors.Seminars in immunopathology · 2020Review
- Prevention of Food Allergy: The Significance of Early Introduction.Medicina (Kaunas, Lithuania) · 2019Review
- Influence of Early Life, Diet, and the Environment on the Microbiome.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Review
- Vitamins A and E during Pregnancy and Allergy Symptoms in an Early Childhood-Lack of Association with Tobacco Smoke Exposure.International journal of environmental research and public health · 2018Article
- Pregnancy diet and offspring asthma risk over a 10-year period: the Lifeways Cross Generation Cohort Study, Ireland.BMJ open · 2018Article
- The First 1000 Days of Life Factors Associated with "Childhood Asthma Symptoms": Brisa Cohort, Brazil.Scientific reports · 2017Article
- Birth by cesarean section and schizophrenia: results from the multicenter FACE-SZ data-set.European archives of psychiatry and clinical neuroscience · 2017Article
- Free 25(OH)D concentrations are associated with atopy and lung function in children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017Article
- Article
- Associations between serum 25(OH)D concentrations and prevalent asthma among children living in communities with differing levels of urbanization: a cross-sectional study.Asthma research and practice · 2017Article
- Predictors of allergen sensitization in Singapore children from birth to 3 years.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A consensus has been reached that the development of allergic disorders is strongly influenced by early life exposures. An overview of several prenatal and early life factors that have been investigated for their associations with development of childhood allergy is presented. Delivery mode, the gut microbiome, vitamin D, folate, breastfeeding, pets, antibiotics, environmental tobacco smoke, and airborne traffic pollutants are discussed. Although many studies suggest an effect, overall, no risk factors clearly increase or reduce the risk of allergic outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.