Evidence map›Paper›PMID 25459096›Full record

Trial reportContraception2015

Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.

Rameet H Singh, Eve Espey, Shannon Carr, Brenda Pereda, Tony Ogburn, Lawrence Leeman

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Contraception, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Local anaesthesia for pain control in first trimester surgical abortion.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rameet H SinghUniversity of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico. Electronic address: RHSingh@salud.unm.edu.
Eve EspeyUniversity of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
Shannon CarrUniversity of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
Brenda PeredaUniversity of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
Tony OgburnUniversity of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
Lawrence LeemanUniversity of New Mexico School of Medicine Department of Family and Community Medicine, Albuquerque, New Mexico.
University of New Mexico · USUniversity of New Mexico Hospital · US

Funding

UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
University of New Mexico Clinical and Translational Science CenterUL1TR000041 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LARSON, RICHARD S · 2012 to 2014
$9.8M
NCATS NIH HHS 8UL1TR000041NCATS NIH HHS UL1 TR000041NCATS NIH HHS UL1 TR001449
6 · The paper itself

Abstract

objectiveThe objective was to determine feasibility of a study comparing mean pain scores between women randomized to nitrous oxide/oxygen (NO) versus oxygen+oral analgesics for trimester surgical abortion. STUDY

designPilot randomized controlled trial comparing NO (n=10) versus oxygen+oral analgesics (n=10). Feasibility of subject recruitment, and pain and satisfaction scores on a visual analog scale were evaluated.

resultsFifty-seven percent of eligible women participated. Mean pain scores were similar between groups, and mean satisfaction scores were higher for the NO group (77.5 vs. 46.7, P=.048).

conclusionsThe majority of eligible women agreed to participate in this study evaluating an uncommon pain control intervention.

Indexed as

Pregnancy Trimester, FirstAbortion, InducedAdministration, OralAdultAnalgesics, Non-NarcoticAnesthetics, InhalationDouble-Blind MethodFeasibility StudiesFemaleHospitals, UniversityHumansIbuprofenNew MexicoNitrous OxideOutpatient Clinics, HospitalOxygen Inhalation TherapyAnalgesics, Non-NarcoticAnesthetics, InhalationIbuprofenNitrous OxideFirst trimesterNitrous oxidePainSurgical abortion

Identifiers

PMID25459096
PMCPMC5317271
OpenAlexW1968459689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.