ArticleAIDS patient care and STDs2015
Disparities in viral load and CD4 count trends among HIV-infected adults in South Carolina.
Article in AIDS patient care and STDs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 39 citations in OpenAlex.
- Reduction in Drinking was Associated With Improved Clinical Outcomes in Women With HIV Infection and Unhealthy Alcohol Use: Results From a Randomized Clinical Trial of Oral Naltrexone Versus Placebo.Alcoholism, clinical and experimental research · 2019Trial
- Acceptability and feasibility of a randomized clinical trial of oral naltrexone vs. placebo for women living with HIV infection: Study design challenges and pilot study results.Contemporary clinical trials · 2017Trial
- Geospatial Accessibility Factors Influencing HIV Care Continuum Outcomes in South Carolina.AIDS and behavior · 2026Article
- Survival analysis of left-truncated and right-censored HIV data: comparison of Cox regression and alternative models.BMC medical research methodology · 2026Article
- Assessing the impact of COVID-19 on HIV care cascade for people living with HIV in Ethiopia: a retrospective longitudinal study.BMJ open · 2024Article
- HIV status and substance use disorder treatment need and utilization among adults in the United States, 2015-2019: Implications for healthcare service provision and integration.Journal of substance use and addiction treatment · 2024Article
- Predictors of Viral Suppression Among People Living with HIV in Rural Oregon.AIDS and behavior · 2024Article
- Distribution of Opportunistic Pathogens in People Living with HIV at a University Hospital in Istanbul over a One-Year Treatment Period and Its Association with CD4 T Cell Counts.Pathogens (Basel, Switzerland) · 2023Article
- Challenges and opportunities for medical referrals at a mobile community health clinic serving sexual and gender minorities in rural South Carolina: a qualitative approach.BMC health services research · 2023Article
- Time to Viral Load Suppression and Its Predictors Among Adult Patients on Antiretro Viral Therapy in Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Southern Ethiopia.HIV/AIDS (Auckland, N.Z.) · 2023Article
- Prevalence and factors associated with substance use among HIV positive youth attending HIV care and treatment centers in Dodoma, Tanzania.AIDS research and therapy · 2022Article
- Family APGAR and treatment outcomes among HIV patients at two ART Centres in Kumasi, Ghana.Ghana medical journal · 2022Article
- Sociodemographic factors affecting viral load suppression among people living with HIV in South Carolina.AIDS care · 2021Article
- Characteristics and treatment outcomes of HIV infected elderly patients enrolled in Kisii Teaching and Referral Hospital, Kenya.African health sciences · 2020Article
- Multilevel ordinal model for CD4 count trends in seroconversion among South Africa women.BMC infectious diseases · 2020Article
- Links between sexual trauma exposure and Quality of Life (QoL) domains among people living with HIV in the Southern United States.AIDS care · 2020Article
- Monitoring HIV infection in Minas Gerais state: 15-year assessment of adults living with HIV initiating Antiretroviral Therapy.Revista da Sociedade Brasileira de Medicina Tropical · 2020Article
- Transgender persons' HIV care (dis)engagement: a qualitative evidence synthesis protocol from an ecological systems theory perspective.BMJ open · 2019Article
- Human immunodeficiency virus-infected young people in Australia: data from the Australian HIV Observational Database.Internal medicine journal · 2018Observational
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
On a population level, trends in viral load (VL) and CD4 cell counts can provide a marker of infectivity and an indirect measure of retention in care. Thus, observing the trend of CD4/VL over time can provide useful information on disparities in populations across the HIV care continuum when stratified by demography. South Carolina (SC) maintains electronic records of all CD4 cell counts and HIV VL measurements reported to the state health department. We examined temporal trends in individual HIV VLs reported in SC between January 1, 2005 and December 31, 2012 by using mixed effects models adjusting for gender, race/ethnicity, age, baseline CD4 count, HIV risk category, and residence. Overall VL levels gradually decreased over the observation period. There were significant differences in the VL decline by gender, age groups, rural/urban residence, and HIV risk exposure group. There were significant differences in CD4 increases by race/ethnicity, age groups, and HIV risk exposure group. However, the population VL declines were slower among individuals aged 13-19 years compared to older age groups (p<0.0001), among men compared to women (p=0.002), and among people living with HIV/AIDS (PLWHA) with CD4 count ≤200 cell/mm(3) compared to those with higher CD4 counts (p<0.0001). Significant disparities were observed in VL decline by gender, age, and CD4 counts among PLWHA in SC. Population based data such as these can help streamline and better target local resources to facilitate retention in care and adherence to medications among PLWHA.
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