ArticleDiabetes research and clinical practice2015
Glucose control in Rwandan youth with type 1 diabetes following establishment of systematic, HbA1c based, care and education.
Article in Diabetes research and clinical practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04272099 (Individual and Social Determinants of Health in Global Pediatric Diabetes Care Delivery - a Participatory Search for Barriers and Opportunities), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Individual and Social Determinants of Health in Global Pediatric Diabetes Care Delivery - a Participatory Search for Barriers and Opportunities
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Longitudinal trends in HbADiabetes/metabolism research and reviews · 2018Pooled it
- Readiness of Sub-Saharan Africa Healthcare Systems for the New Pandemic, Diabetes: A Systematic Review.Journal of diabetes research · 2018Pooled it
- Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus.The Kaohsiung journal of medical sciences · 2026Article
- A Study Protocol for a Randomized, Controlled Trial: Improving Glucose Time-in-Range in Diabetes in African Youth (DAYTime).Methods and protocols · 2026Article
- Evaluation of care and clinical outcomes after the implementation of an electronic medical record system for type 1 diabetes management in Rwanda.Global health action · 2025Article
- Models of care for children and adolescents with type 1 diabetes in low- and middle-income countries: a scoping review.The Cochrane database of systematic reviews · 2025Article
- The Development of an Electronic Medical Record System to Improve Quality of Care for Individuals With Type 1 Diabetes in Rwanda: Qualitative Study.JMIR diabetes · 2024Article
- Using e-modules for acquisition of complex diabetes skills in diabetes care providers in Rwanda.PLOS global public health · 2024Article
- Impact of Sleep and Activity on Glycemic Control and Quality of Life in Haitian Children and Youth with Type 1 Diabetes.Pediatric diabetes · 2023Article
- Heterogeneous long-term trajectories of glycaemic control in type 1 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2021Article
- Prediction of prevalence of type 2 diabetes in Rwanda using the metropolis-hasting sampling.African health sciences · 2021Article
- Continuous glucose monitoring assessment of metabolic control in east African children and young adults with type 1 diabetes: A pilot and feasibility study.Endocrinology, diabetes & metabolism · 2020Article
- Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study.Annals of global health · 2020Article
- Early Diabetic Nephropathy and Retinopathy in Patients with Type 1 Diabetes Mellitus Attending Sudan Childhood Diabetes Centre.Journal of diabetes research · 2020Article
- Clinical profile of diabetes at diagnosis among children and adolescents at an endocrine clinic in Ghana.World journal of diabetes · 2017Article
- Exercise-induced albuminuriaWorld journal of diabetes · 2017Article
- Recommendations and Standardization of Biomarker Quantification Using NMR-Based Metabolomics with Particular Focus on Urinary Analysis.Journal of proteome research · 2016Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
aimsTo assess change in glycemic control concurrent with increased clinic visits, HbA1c testing, and education. Rates of complications were also examined.
methodsA 1-2 year follow-up of 214 members of the Rwanda Life for a Child program (aged <26 years) with a first HbA1c between June 2009 and November 2010 was conducted. Data were analyzed for the entire cohort and by age (<18 years, ≥18 years). Trajectory analysis was performed to identify trends in HbA1c.
resultsMean overall HbA1c decreased significantly from baseline (11.2 ± 2.7%; 99 ± 30 mmol/mol) to one- (10.2 ± 2.6%; 88 ± 28 mmol/mol) and two- (9.8 ± 26%; 84 ± 25 mmol/mol) year follow up visits. The prevalence of microalbuminuria did not significantly change (21.0%, 18.8%, and 19.6%), nor did nephropathy (4.7%, 7.8%, and 5.4%). However, rates of hypertension (31.8%, 44.9%, and 40.3%) were higher than expected. Five HbA1c groups were identified by trajectory analysis, and those with the worst control monitored their glucose significantly fewer times per week.
conclusionsThe establishment of regular care, HbA1c testing, and increased education is associated with significant improvements in glycemic control in youth with type 1 diabetes (T1D) in sub-Saharan Africa, but the high prevalence of hypertension is of concern.
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