Evidence map›Paper›PMID 25458258›Full record

ArticleBrazilian journal of otorhinolaryngology

Papillary thyroid carcinoma: does the association with Hashimoto's thyroiditis affect the clinicopathological characteristics of the disease?

Fábio Muradás Girardi, Marinez Bizarro Barra, Cláudio Galleano Zettler

Open access · goldAbstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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  14. Expressions of IL-17 and TNF-α in patients with Hashimoto's disease combined with thyroid cancer before and after surgery and their relationship with prognosis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
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  20. Analysis of Malignant Thyroid Neoplasms with a Striking Rise of Papillary Microcarcinoma in an Endemic Goiter Region.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fábio Muradás GirardiHead and Neck Surgery Department, Hospital Santa Rita, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address: fabiomgirardi@gmail.com.
Marinez Bizarro BarraPathology Department, Hospital Santa Rita, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil.
Cláudio Galleano ZettlerPathology Department, Hospital Santa Rita, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil.
Santa Casa Hospital · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPapillary carcinoma is the most common malignant thyroid neoplasm. The effect of the concurrent presence of Hashimoto's thyroiditis and papillary thyroid carcinoma remains controversial.

objectiveTo evaluate the association between Hashimoto's thyroiditis and clinicopathological parameters in thyroid papillary carcinoma cases, based on an historical institutional cohort analysis.

methodsCross-sectional study obtained from a historical cohort, including all cases submitted to thyroidectomy for papillary thyroid carcinoma in a single institution during an 11-year period study.

resultsA total of 417 patients with papillary thyroid carcinoma were enrolled; 148 (35.4%) also had Hashimoto's thyroiditis. A female predominance among cases associated to Hashimoto's thyroiditis was observed. The thyroid tumor, in cases associated with Hashimoto's thyroiditis, had a smaller mean diameter, lower frequency of extra-thyroid extension, and earlier clinicopathological staging.

conclusionsA high proportion of papillary thyroid carcinoma cases are associated with Hashimoto's thyroiditis. There are associations among these cases with several histopathological factors already recognized for their prognostic value, which by themselves could impact outcomes.

Indexed as

AdolescentAdultAgedAged, 80 and overCarcinoma, PapillaryCross-Sectional StudiesFemaleHashimoto DiseaseHumansMaleMiddle AgedSex FactorsThyroidectomyThyroid NeoplasmsYoung AdultCarcinoma papilarNeoplasias da glândula tireoidePapillary carcinomaPrognosisPrognósticoThyroid neoplasms

Identifiers

PMID25458258
PMCPMC9452232
OpenAlexW2030361881

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.