Evidence map›Paper›PMID 25458254›Full record

ArticleBrazilian journal of otorhinolaryngology

Brainstem auditory evoked potentials in children with lead exposure.

Katia de Freitas Alvarenga, Thais Catalani Morata, Andrea Cintra Lopes, Mariza Ribeiro Feniman, Lilian Cassia Bornia Jacob Corteletti

Open access · goldAbstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. A review of the auditory-gut-brain axis.Frontiers in neuroscience · 2023
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Low-level prenatal lead exposure and infant sensory function.Environmental health : a global access science source · 2016
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Katia de Freitas AlvarengaDepartment of Speech Therapy and Audiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB-USP), Bauru, SP, Brazil.
Thais Catalani MorataNational Institute for Occupational Safety and Health (NIOSH), Division of Applied Research and Technology, Cincinnati, OH, United States.
Andrea Cintra LopesDepartment of Speech Therapy and Audiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB-USP), Bauru, SP, Brazil.
Mariza Ribeiro FenimanDepartment of Speech Therapy and Audiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB-USP), Bauru, SP, Brazil.
Lilian Cassia Bornia Jacob CortelettiDepartment of Speech Therapy and Audiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB-USP), Bauru, SP, Brazil. Electronic address: lilianjacob@fob.usp.br.
Universidade de São Paulo · BRNational Institute for Occupational Safety and Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionEarlier studies have demonstrated an auditory effect of lead exposure in children, but information on the effects of low chronic exposures needs to be further elucidated.

objectiveTo investigate the effect of low chronic exposures of the auditory system in children with a history of low blood lead levels, using an auditory electrophysiological test.

methodsContemporary cross-sectional cohort. Study participants underwent tympanometry, pure tone and speech audiometry, transient evoked otoacoustic emissions, and brainstem auditory evoked potentials, with blood lead monitoring over a period of 35.5 months. The study included 130 children, with ages ranging from 18 months to 14 years, 5 months (mean age 6 years, 8 months ± 3 years, 2 months).

resultsThe mean time-integrated cumulative blood lead index was 12 μg/dL (SD ± 5.7, range: 2.433). All participants had hearing thresholds equal to or below 20 dBHL and normal amplitudes of transient evoked otoacoustic emissions. No association was found between the absolute latencies of waves I, III, and V, the interpeak latencies I-III, III-V, and I-V, and the cumulative lead values.

conclusionNo evidence of toxic effects from chronic low lead exposures was observed on the auditory function of children living in a lead contaminated area.

Indexed as

Acoustic Impedance TestsAdolescentAudiometry, Pure-ToneAudiometry, SpeechChildChild, PreschoolCross-Sectional StudiesEvoked Potentials, Auditory, Brain StemFemaleHearing TestsHumansInfantLeadMaleOtoacoustic Emissions, SpontaneousTime FactorsLeadAudiometria de tons purosBrainstem auditory evoked potentialsIntoxicação por chumboLead poisoningPotenciais evocados auditivos do tronco encefálicoPure-tone audiometryToxicidadeToxicity

Identifiers

PMID25458254
PMCPMC4557785
OpenAlexW2138015130

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.