Evidence map›Paper›PMID 25457926›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2014

Effects of multidimensional treatment foster care on psychotic symptoms in girls.

Richie Poulton, Mark J Van Ryzin, Gordon T Harold, Patricia Chamberlain, David Fowler, Mary Cannon, Louise Arseneault, Leslie D Leve

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01341626 (Juvenile Justice Girls), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01341626 nacompletednot on this map

Juvenile Justice Girls: Pathways to Adjustment and System Use in Young Adulthood

TypeinterventionalSponsorOregon Social Learning CenterRan1997 to 2016Enrolled166ConditionsDelinquency, Drug UseArmsTreatment Foster Care (TFCO), Group Care
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. The Landscape of Randomized Controlled Trials for Behavioral Health-Focused Psychosocial Interventions for Youth in the Juvenile Legal System: A Systematic Review.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025
    Article
  3. Exploring causal mechanisms of psychosis risk.Neuroscience and biobehavioral reviews · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Does the Fast Track Intervention Prevent Later Psychosis Symptoms?Prevention science : the official journal of the Society for Prevention Research · 2019
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Delinquency, depression, and psychosis among adolescents in foster care: what holds three heads together?Journal of the American Academy of Child and Adolescent Psychiatry · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Richie PoultonDunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, New Zealand.
Mark J Van RyzinOregon Social Learning Center, Eugene, OR.
Gordon T HaroldSchool of Psychology, University of Sussex, UK; Institute of Genetic Neurobiological and Social Foundations of Child Development, Tomsk State University, Tomsk, Russia; and the MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, Wales.
Patricia ChamberlainOregon Social Learning Center, Eugene, OR.
David FowlerSchool of Psychology, University of Sussex, Brighton, UK.
Mary CannonRoyal College of Surgeons in Dublin and Beaumont Hospital, Dublin.
Louise ArseneaultInstitute of Psychiatry, King's College London.
Leslie D LeveUniversity of Oregon and the Oregon Social Learning Center. Electronic address: leve@uoregon.edu.
Oregon Social Learning Center · USCardiff University · GBKing's College London · GBRoyal College of Surgeons of England · GBUniversity of Otago · NZUniversity of Sussex · GB

Funding

Translational Drug Abuse Prevention CenterP50DA035763 · NIDA · OREGON SOCIAL LEARNING CENTER, INC. · PI CHAMBERLAIN, PATRICIA, FISHER, PHILIP A · 2013 to 2017
$9.5M
Preventing Problems for Girls in Foster CareR01MH054257 · NIMH · OREGON SOCIAL LEARNING CENTER, INC. · PI LEVE, LESLIE DIANE · 1997 to 2008
$3.9M
Preventing Health-Risking Behaviors in Delinquent GirlsR01DA015208 · NIDA · OREGON SOCIAL LEARNING CENTER, INC. · PI CHAMBERLAIN, PATRICIA · 2002 to 2006
$3.3M
Juvenile Justice Girls: Pathways to Adjustment and System Use in Young AdulthoodR01DA024672 · NIDA · OREGON SOCIAL LEARNING CENTER, INC. · PI LEVE, LESLIE DIANE · 2009 to 2012
$2.3M
NIDA NIH HHS P50 DA035763NIDA NIH HHS R01 DA015208NIDA NIH HHS R01 DA024672NIMH NIH HHS R01 MH054257
6 · The paper itself

Abstract

objectiveNeurodevelopmental theories of psychosis highlight the potential benefits of early intervention, prevention, and/or preemption. How early intervention should take place has not been established, nor whether interventions based on social learning principles can have preemptive effects. The objective was to test whether a comprehensive psychosocial intervention can significantly alter psychotic symptom trajectories during adolescence-a period of heightened risk for a wide range of psychopathology.

methodThis study was a randomized controlled trial (RCT) of Multidimensional Treatment Foster Care (MTFC) for delinquent adolescent girls. Assessment of psychotic symptoms took place at baseline and then 6, 12, 18, and 24 months post-baseline using a standardized self-report instrument (Brief Symptom Inventory). A second source of information about psychotic symptoms was obtained at baseline or 12 months, and again at 24 months using a structured diagnostic interview (the Diagnostic Interview Schedule for Children [DISC]).

resultsSignificant benefits for MTFC over treatment as usual for psychosis symptoms were observed over a 24-month period. Findings were replicated across both measures. Effects were independent of substance use and initial symptom severity and persisted beyond the initial intervention period.

conclusionAmeliorating nonclinical psychotic symptoms trajectories beginning in mid-adolescence via a multifaceted psychosocial intervention is possible. Developmental research on nonclinical psychotic symptoms and their prognostic value should be complemented by more psychosocial intervention research aimed at modifying these symptom trajectories early in their natural history. Clinical trial registration information-Juvenile Justice Girls Randomized Control Trial: Young Adult Follow-up; http://clinicaltrials.gov; NCT01341626.

Indexed as

AdolescentCommunity Mental Health ServicesFemaleFoster Home CareHumansJuvenile DelinquencyPsychotherapyPsychotic DisordersTreatment Outcomegirlsjuvenile justiceMTFCpsychotic symptomsRCT

Identifiers

PMID25457926
PMCPMC4254696
OpenAlexW2005711522

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.