Evidence map›Paper›PMID 25457753›Full record

ReviewAlcohol (Fayetteville, N.Y.)2015

Assessing ethanol's actions in the suprachiasmatic circadian clock using in vivo and in vitro approaches.

Rebecca A Prosser, J David Glass

Abstract readReview
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Alcohol and Opioids Modulate Excitatory Inputs to the SCN.bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Emerging role of circadian clock disruption in alcohol-induced liver disease.American journal of physiology. Gastrointestinal and liver physiology · 2018
    Review
  9. Review
  10. Neural plasticity · 2017
    Review
  11. Review
  12. A single dose of alcohol does not meaningfully alter circadian phase advances and phase delays to light in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2016
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rebecca A Prosser *Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.
J David Glass *Department of Biological Sciences, Kent State University, Kent, OH 44242, USA.

Funding

Ethanol Effects on the Mammalian Circadian ClockR01AA017898 · NIAAA · UNIVERSITY OF TENNESSEE KNOXVILLE · PI GLASS, JOHN DAVID, PROSSER, REBECCA A · 2010 to 2013
$1.3M
Ethanol Effects in the Mammalian Circadian ClockR21AA015948 · NIAAA · UNIVERSITY OF TENNESSEE KNOXVILLE · PI PROSSER, REBECCA A · 2007 to 2008
$379k
NIAAA NIH HHS R01 AA017898NIAAA NIH HHS R21 AA015948
6 · The paper itself

Abstract

Research over the past decade has demonstrated substantial interactions between the circadian system and the processes through which alcohol affects behavior and physiology. Here we summarize the results of our collaborative efforts focused on this intersection. Using a combination of in vivo and in vitro approaches, we have shown that ethanol affects many aspects of the mammalian circadian system, both acutely as well as after chronic administration. Conversely, we have shown circadian influences on ethanol consumption. Importantly, we are beginning to delve into the cellular mechanisms associated with these effects. We are also starting to form a picture of the neuroanatomical bases for many of these actions. Finally, we put our current findings into perspective by suggesting new avenues of inquiry for our future efforts.

Indexed as

AnimalsCentral Nervous System DepressantsCircadian ClocksEthanolgamma-Aminobutyric AcidGlutamic AcidHumansIn Vitro TechniquesSerotoninSuprachiasmatic NucleusCentral Nervous System DepressantsEthanolgamma-Aminobutyric AcidGlutamic AcidSerotoninCircadian rhythmsEthanolGABAGlutamateSerotoninSuprachiasmatic nucleus

Identifiers

PMID25457753
PMCPMC4402095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.