Evidence map›Paper›PMID 25456014›Full record

Trial reportHealth & place2014

Neighborhood effects in a behavioral randomized controlled trial.

Sandi L Pruitt, Tammy Leonard, James Murdoch, Amy Hughes, Amy McQueen, Samir Gupta

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Health & place, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandi L PruittDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA; Harold C. Simmons Comprehensive Cancer Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9169, USA. Electronic address: Sandi.Pruitt@utsouthwestern.edu.
Tammy LeonardEconomics Department, University of Dallas, 1845 E. Northgate Dr., Irving, TX 75026, United States.
James MurdochSchool of Economic, Political, and Policy Sciences, University of Texas-Dallas, 800W. Campbell Rd, GR31, Richardson, TX 75080, USA.
Amy HughesDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA; School of Economic, Political, and Policy Sciences, University of Texas-Dallas, 800W. Campbell Rd, GR31, Richardson, TX 75080, USA.
Amy McQueenDivision of Health Behavior Research, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue Campus, Box 8005, St. Louis, MO 63110, USA.
Samir GuptaDivision of Gastroenterology, Department of Internal Medicine, Moores Cancer Center, University of California, San Diego, CA, USA; Department of Veterans Affairs, San Diego Healthcare System, 3350 La Jolla Village Dr MC 111D, San Diego, CA 92161, USA.

Funding

NIMHD NIH HHS L60 MD003664
6 · The paper itself

Abstract

Randomized controlled trials (RCTs) of interventions intended to modify health behaviors may be influenced by neighborhood effects which can impede unbiased estimation of intervention effects. Examining a RCT designed to increase colorectal cancer (CRC) screening (N=5628), we found statistically significant neighborhood effects: average CRC test use among neighboring study participants was significantly and positively associated with individual patient's CRC test use. This potentially important spatially-varying covariate has not previously been considered in a RCT. Our results suggest that future RCTs of health behavior interventions should assess potential social interactions between participants, which may cause intervention arm contamination and may bias effect size estimation.

Indexed as

Health BehaviorPatient Acceptance of Health CareResidence CharacteristicsColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMiddle AgedCancer screeningNeighborhoodPeer relationshipsRandomized controlled trialSpatial autocorrelation

Identifiers

PMID25456014
PMCPMC4845650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.