ArticlePhysiology & behavior2015
Children's cortisol and salivary alpha-amylase interact to predict attention bias to threatening stimuli.
Article in Physiology & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Adrenocortical and autonomic cross-system regulation in youth: A meta-analysis.Psychoneuroendocrinology · 2024Pooled it
- Research prospect of human salivary cortisol: a bibliometric analysis.Frontiers in psychology · 2025Review
- Association among childhood adversity and susceptibility to interference during varying salience: two studies in healthy males.Scientific reports · 2024Article
- Improved Reliability of Dot Probe Measures with Response-Based Computation: An Application with Young Violence-Exposed Children.Cognitive therapy and research · 2023Article
- Exploring joint HPA-inflammatory stress response profiles in adolescent girls: Implications for developmental models of neuroendocrine dysregulation.Developmental psychobiology · 2022Article
- Youths' processing of emotion information: Responses to chronic and video-based laboratory stress.Psychoneuroendocrinology · 2020Article
- Chronic Stress in Children and Adolescents: A Review of Biomarkers for Use in Pediatric Research.Biological research for nursing · 2018Article
- Person-centered examination of salivary cortisol and alpha-amylase responses to psychosocial stress: Links to preadolescent behavioral functioning and coping.Biological psychology · 2018Article
- Neural Correlates of Drug-Related Attentional Bias in Heroin Dependence.Frontiers in human neuroscience · 2017Article
- Attentional biases to emotional stimuli: Key components of the RDoC constructs of sustained threat and loss.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Physiological responses to threat occur through both the autonomic nervous system (ANS) and the hypothalamic pituitary adrenal (HPA) axis. Activity in these systems can be measured through salivary alpha-amylase (sAA) and salivary cortisol, respectively. Theoretical work and empirical studies have suggested the importance of examining the coordination of these systems in relation to cognitive functioning and behavior problems. Less is known, however, about whether these systems interactively predict more automatic aspects of attention processing such as attention toward emotionally salient threatening stimuli. We used a dot probe task to assess attention bias toward threatening stimuli in 347 kindergarten children. Cortisol and sAA were assayed from saliva samples collected prior to children's participation in assessments on a subsequent day. Using regression analyses, we examined relations of sAA and cortisol to attention bias. Results indicate that cortisol and sAA interact in predicting attention bias. Higher levels of cortisol predicted greater bias toward threat for children who had high levels of sAA, but predicted greater bias away from threat for children who had low levels of sAA. These results suggest that greater symmetry in HPA and ANS functioning is associated with greater reliance on automatic attention processes in the face of threat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.