Evidence map›Paper›PMID 25455711›Full record

ArticleEuropean journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society2015

Antecedents and correlates of visual field deficits in children born extremely preterm.

Mari Holm, Michael E Msall, Jon Skranes, Olaf Dammann, Elizabeth Allred, Alan Leviton

Abstract read
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Article in European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. The neural retina in retinopathy of prematurity.Progress in retinal and eye research · 2017
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mari HolmDepartment of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, N-7489 Trondheim, Norway; Department of Public Health and Community Medicine, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA. Electronic address: mari.holm@ntnu.no.
Michael E MsallDepartment of Pediatrics, Section of Developmental and Behavioral Pediatrics and JP Kennedy Research Center on Intellectual and Developmental Disabilities, University of Chicago Comer Children's Hospital, 5721 S. Maryland Avenue, Chicago, IL 60637, USA. Electronic address: mmsall@peds.bsd.uchicago.edu.
Jon SkranesDepartment of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, N-7489 Trondheim, Norway. Electronic address: jon.skranes@ntnu.no.
Olaf DammannDepartment of Public Health and Community Medicine, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA; Neuroepidemiology Unit, Hannover School of Medicine, Hannover, Germany. Electronic address: olaf.dammann@tufts.edu.
Elizabeth AllredNeurology Departments, Boston Children's Hospital, and Harvard Medical School, Au-414 300 Longwood Avenue, Boston, MA 02115-5724, USA. Electronic address: lizard@hsph.harvard.edu.
Alan LevitonNeurology Departments, Boston Children's Hospital, and Harvard Medical School, Au-414 300 Longwood Avenue, Boston, MA 02115-5724, USA. Electronic address: alan.leviton@childrens.harvard.edu.

Funding

Neonatal Biomarkers in Extremely Preterm Babies Predict Childhood Brain DisordersU01NS040069 · NINDS · CHILDREN'S HOSPITAL BOSTON · PI KUBAN, KARL · 2001 to 2014
$34.0M
SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Placenta bacteriology and histology in the etiology of retinopathy of prematurityR21EY019253 · NEI · TUFTS MEDICAL CENTER · PI DAMMANN, OLAF · 2009 to 2010
$466k
NCATS NIH HHS UL1 TR000430NEI NIH HHS 1R21EY019253-01NEI NIH HHS R21 EY019253NICHD NIH HHS 5P30HD018655-28NICHD NIH HHS P30 HD018655NINDS NIH HHS 2R01NS040069-06A2NINDS NIH HHS 5U01NS040069-05NINDS NIH HHS U01 NS040069
6 · The paper itself

Abstract

aimWe sought to identify the antecedents and correlates of visual field deficits (VFDs) at age 2 years among infants born before the 28th week of gestation.

methodsThe visual fields of 1023 infants were assessed by confrontation at age 2 years. We compared the ante-and postnatal characteristics and exposures of the 65 infants with a VFD to their peers who did not have a VFD. We used time-oriented logistic regression risk models to assess the associations of potential antecedents and correlates with a VFD.

resultsIn the final regression model, VFD was associated with maternal consumption of aspirin during the current pregnancy, recurring/persistent acidemia during the first 3 postnatal days, cerebral ventriculomegaly seen on neonatal ultrasound, prethreshold retinopathy of prematurity (ROP), and supplemental oxygen and ventilator dependence at 36 weeks post-menstrual age. Birth before the 27th week was also associated with increased risk, but its significance was diminished by the addition of postnatal variables.

conclusionIn this sample of extremely preterm born infants, antenatal as well as early and late postnatal characteristics and exposures are associated with an increased risk of having a VFD. Our study adds to our knowledge about the complex etiology of visual deficits of prematurity, and supports a multifactorial cause of these deficits.

Indexed as

Infant, Extremely PrematureVisual FieldsAcidosisAdultAnti-Inflammatory Agents, Non-SteroidalAspirinCerebral VentriclesChild DevelopmentFemaleGestational AgeHumansInfantInfant, NewbornMaleOxygen Inhalation TherapyPlacentaAnti-Inflammatory Agents, Non-SteroidalAspirinBrain developmentPrematurityPreterm birthROPVentriculomegalyVisual field deficits

Identifiers

PMID25455711
PMCPMC4276499

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.