ReviewTrends in cardiovascular medicine2015
Microvascular coronary dysfunction and ischemic heart disease: where are we in 2014?
Review in Trends in cardiovascular medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- High-Volume Acquisition Rate Nonlinear Imaging Enables Robust 3-D Ultrasound Localization Microscopy.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- Advances in the diagnosis and management of post-percutaneous coronary intervention coronary microvascular dysfunction: Insights into pathophysiology and metabolic risk interactions.World journal of cardiology · 2025Review
- HuR/Cx40 downregulation causes coronary microvascular dysfunction in type 2 diabetes.JCI insight · 2021Article
- Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion.Theranostics · 2021Article
- Left ventricular ischemia in pre-capillary pulmonary hypertension: a cardiovascular magnetic resonance study.Cardiovascular diagnosis and therapy · 2020Article
- Coronary Microvascular Dysfunction and the Role of Noninvasive Cardiovascular Imaging.Diagnostics (Basel, Switzerland) · 2020Review
- Blood Oxygen Level-Dependent MRI of the Myocardium with Multiecho Gradient-Echo Spin-Echo Imaging.Radiology · 2020Article
- Sexual Dimorphism of Coronary Artery Disease in a Low- and Intermediate-Risk Asymptomatic Population: Association with Coronary Vessel Wall Thickness at MRI in Women.Radiology. Cardiothoracic imaging · 2019Article
- Interrelationship in the prognostic efficacy of regional coronary flow reserve, fractional flow reserve, high-sensitivity cardiac troponin-I and NT-proBNP in patients with stable coronary artery disease.Heart and vessels · 2019Article
- Non-invasive measures of coronary microcirculation: Taking the long road to the clinic.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis.Scientific reports · 2018Article
- Reactive hyperemia is associated with adverse clinical outcomes in heart failure.American heart journal · 2016Article
- Tongxinluo Reverses the Hypoxia-suppressed Claudin-9 in Cardiac Microvascular Endothelial Cells.Chinese medical journal · 2016Article
- Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation.Circulation research · 2015Article
- The role of coronary microvascular disorder in congestive heart failure.American journal of physiology. Heart and circulatory physiology · 2015Article
- Restoration of coronary microvascular function by OGA overexpression in a high-fat diet with low-dose streptozotocin-induced type 2 diabetic mice.Diabetes & vascular disease researchArticle
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2 authors at 1 institution in 1 country.
Funding
Abstract
Many patients with angina and signs of myocardial ischemia on stress testing have no significant obstructive epicardial coronary disease. There are many potential coronary and non-coronary mechanisms for ischemia without obstructive epicardial coronary disease, and prominent among these is coronary microvascular and/or endothelial dysfunction. Patients with coronary microvascular and/or endothelial dysfunction are often at increased risk of adverse cardiovascular events, including ischemic events and heart failure despite preserved ventricular systolic function. In this article, we will review the diagnosis and treatment of coronary microvascular and endothelial dysfunction, discuss their potential contribution to heart failure with preserved ejection fraction, and highlight recent advances in the evaluation of atherosclerotic morphology in these patients, many of whom have non-obstructive epicardial disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.