ReviewOsteoarthritis and cartilage2015
Smoking and osteoarthritis: a review of the evidence and its implications.
Review in Osteoarthritis and cartilage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of smoking with knee osteoarthritis structural defects and symptoms: an individual participant data meta-analysis.Scientific reports · 2024Pooled it
- Body mass index and risk of lung cancer: Systematic review and dose-response meta-analysis.Scientific reports · 2015Pooled it
- Cigarette Smoke Extract Alters the Inflammatory Secretome of Osteoarthritis-Affected Synovium Increasing Joint Tissue Oxidative Stress in an Indirect Co-Culture Model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Nicotine use is Associated With Elevated Risk of Opioid use Disorder Following Total/Hemi Hip Arthroplasty Procedures.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Cigarette and Electronic Cigarette Exposure in Osteoarthritis: Immune Dysregulation and Inflammatory Signaling Pathways.International journal of general medicine · 2026Article
- Association between urinary NNAL concentrations and osteoarthritis: Evidence from NHANES 2007-2012.Tobacco induced diseases · 2026Article
- Cannabis Use and Analgesic Prescribing in UK Primary Care: A Retrospective Cohort Study of Patients with Osteoarthritis.Medicines (Basel, Switzerland) · 2025Article
- Article
- Associations between surrogate insulin resistance indexes and osteoarthritis: NHANES 2003-2016.Scientific reports · 2025Article
- Life's Essential 8 and its association with osteoarthritis and disability: a cross-sectional study based on the NHANES 2005-2018 database.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Comparative study on the association between types of physical activity, physical activity levels, and the incidence of osteoarthritis in adults: the NHANES 2007-2020.Scientific reports · 2024Article
- Association between Low Serum Creatinine Levels and Knee Osteoarthritis in Koreans without Renal Insufficiency.Yonsei medical journal · 2024Article
- Intra-articular steroids for the treatment of coxarthrosis; a retrospective cohort study comparing three contrast techniques.Archives of orthopaedic and trauma surgery · 2024Article
- Factors associated with trajectories of bone marrow lesions over 4 years: data from the Osteoarthritis Initiative.Skeletal radiology · 2024Article
- Systemic inflammatory biomarkers are novel predictors of all-cause and cardiovascular mortality in individuals with osteoarthritis: a prospective cohort study using data from the NHANES.BMC public health · 2024Article
- An in-depth analysis of young adults with osteonecrosis secondary to developmental dysplasia of the hip who underwent total hip arthroplasty.BMC musculoskeletal disorders · 2024Article
- Lifestyle behaviour changes associated with osteoarthritis: a prospective cohort study.Scientific reports · 2024Article
- Association between higher triglyceride glucose index and increased risk of osteoarthritis: data from NHANES 2015-2020.BMC public health · 2024Article
- Investigation of the Associations of Smoking With Hip Osteoarthritis: A Baseline Cross-Sectional and Four- to Five-Year Longitudinal Multicohort Study.ACR open rheumatology · 2024Article
- Smoking-diseases correlation database: comprehensive analysis of the correlation between smoking and 422 diseases based on NHANES 2013-2018.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
A number of reports including a recent publication in Osteoarthritis and Cartilage have suggested that smokers have a lower than expected prevalence of osteoarthritis (OA) than nonsmokers. We review the evidence linking smoking with OA, suggest approaches whereby the direct and indirect effects of smoking on OA might be distinguished, highlight two diseases, ulcerative colitis and Parkinson's disease, where smoking is protective, discuss mechanisms by which nicotine might act and lastly explore the association of smoking with enhanced musculoskeletal pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.