Evidence map›Paper›PMID 25454290›Full record

ArticleJournal of psychosomatic research2014

Are children and adolescents with food allergies at increased risk for psychopathology?

Lilly Shanahan, Nancy Zucker, William E Copeland, E Jane Costello, Adrian Angold

Open access · greenAbstract read
In one paragraph

Article in Journal of psychosomatic research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Fear and picky eating-related ARFID behaviors in children with food allergy.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Food Allergy and Mental Health in Children and Adolescents-The Role of Shared Familial Environment.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Article
  10. Review
  11. Anxiety among youth with food allergy.Journal of pediatric psychology · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Psychological impacts of coronavirus disease 2019 on people with asthma, allergic rhinitis, and food allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Food Allergy, Eating Disorders and Body Image.Journal of affective disorders reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lilly ShanahanUniversity of North Carolina at Chapel Hill, United States. Electronic address: lilly_shanahan@unc.edu.
Nancy ZuckerDevelopmental Epidemiology Program, Duke University Medical Center, United States; Duke Center for Eating Disorders, United States.
William E CopelandDevelopmental Epidemiology Program, Duke University Medical Center, United States.
E Jane CostelloDevelopmental Epidemiology Program, Duke University Medical Center, United States.
Adrian AngoldDevelopmental Epidemiology Program, Duke University Medical Center, United States.
Duke University Hospital · USDuke Medical Center · US

Funding

TRANSLATION AND DISSEMINATION COREP30DA023026 · NIDA · DUKE UNIVERSITY · PI HOYLE, RICK · 2008 to 2023
$19.6M
NCANDA Research Project Site: DukeU01AA021681 · NIAAA · DUKE UNIVERSITY · PI DAVID B. GOLDSTON · 2012 to 2026
$9.8M
A Developmental Model of Gene-Environment Interplay in SUDsU01DA024413 · NIDA · DUKE UNIVERSITY · PI COSTELLO, ELIZABETH JANE · 2007 to 2010
$7.7M
Vulnerability to Drug Abuse:Pathways to RecoveryR01DA011301 · NIDA · DUKE UNIVERSITY · PI COSTELLO, ELIZABETH JANE · 1997 to 2015
$7.3M
Pathways from Childhood Self-Regulation to Cardiovascular Risk in AdolescenceR01HD078346 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WIDEMAN, LAURIE · 2014 to 2018
$3.7M
Prefrontal Function in Adolescent Limited vs Life Course Persistent SUDR01DA022308 · NIDA · DUKE UNIVERSITY · PI DE BELLIS, MICHAEL DAMINGO · 2008 to 2012
$3.0M
Prepubertal Comordity: Gender &Developmental HeterotypyR01MH063671 · NIMH · DUKE UNIVERSITY · PI COSTELLO, ELIZABETH JANE · 2001 to 2005
$2.3M
Growing Up Violent in Rural AmericaR01MH063970 · NIMH · DUKE UNIVERSITY · PI COSTELLO, ELIZABETH JANE · 2002 to 2006
$1.6M
A Developmental Model of Gene-Environment Interplay in SUDsR01DA024413 · NIDA · DUKE UNIVERSITY · PI COSTELLO, ELIZABETH JANE · 2011 to 2011
$1.2M
Feelings/Body Investigators:Interoceptive Exposure for Children w/Abdominal PainR33MH097959 · NIMH · DUKE UNIVERSITY · PI ZUCKER, NANCY L · 2016 to 2018
$819k
Early Substance Use in Rural American Indian and White/Anglo YouthR01DA036523 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COPELAND, WILLIAM · 2014 to 2016
$700k
Feelings/Body Investigators:Interoceptive Exposure for Children w/Abdominal PainR21MH097959 · NIMH · DUKE UNIVERSITY · PI EGGER, HELEN L., ZUCKER, NANCY L · 2013 to 2014
$495k
NIAAA NIH HHS U01 AA021681NICHD NIH HHS R01 HD078346NIDA NIH HHS DA/MH11301NIDA NIH HHS P30 DA023026NIDA NIH HHS R01 DA011301NIDA NIH HHS R01 DA022308NIDA NIH HHS R01 DA024413NIDA NIH HHS R01 DA036523NIDA NIH HHS U01 DA024413NIMH NIH HHS MH094605NIMH NIH HHS MH63671NIMH NIH HHS MH63970NIMH NIH HHS R01 MH048085NIMH NIH HHS R01 MH063671NIMH NIH HHS R01 MH063970NIMH NIH HHS R03 MH094605NIMH NIH HHS R21 MH097959NIMH NIH HHS R33 MH097959
6 · The paper itself

Abstract

objectiveLiving with food allergy is a unique and potentially life-threatening stressor that requires constant vigilance to food-related stimuli, but little is known about whether adolescents with food allergies are at increased risk for psychopathology-concurrently and over time.

methodsData came from the prospective-longitudinal Great Smoky Mountains Study. Adolescents (N=1420) were recruited from the community, and interviewed up to six times between ages 10 and 16 for the purpose of the present analyses. At each assessment, adolescents and one parent were interviewed using the Child and Adolescent Psychiatric Assessment, resulting in N=5165 pairs of interviews.

resultsCross-sectionally, food allergies were associated with more symptoms of separation and generalized anxiety, disorder, attention deficit and hyperactivity disorder, and anorexia nervosa. Longitudinally, adolescents with food allergy experienced increases in symptoms of generalized anxiety disorder and depression from one assessment to the next. Food allergies were not, however, associated with a higher likelihood of meeting diagnostic criteria for a psychiatric disorder.

conclusionThe unique constellation of adolescents' increased symptoms of psychopathology in the context of food allergy likely reflects an adaptive increase in vigilance rather than cohesive syndromes of psychopathology. Support and guidance from health care providers is needed to help adolescents with food allergies and their caregivers achieve an optimal balance between necessary vigilance and hypervigilance and unnecessary restriction.

Indexed as

AdolescentAnorexia NervosaAnxietyAttention Deficit Disorder with HyperactivityChildComorbidityDepressionDepressive DisorderFemaleFood HypersensitivityHumansLongitudinal StudiesMaleMental DisordersProspective StudiesPsychopathologyAdolescenceAnxietyDepressionEating disordersFood allergyPsychopathologyStressors

Identifiers

PMID25454290
PMCPMC4307934
OpenAlexW2168679122

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.